3ino

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Current revision (07:54, 6 September 2023) (edit) (undo)
 
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<StructureSection load='3ino' size='340' side='right'caption='[[3ino]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
<StructureSection load='3ino' size='340' side='right'caption='[[3ino]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3ino]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_cereus_var._anthracis"_(cohn_1872)_smith_et_al._1946 "bacillus cereus var. anthracis" (cohn 1872) smith et al. 1946]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3INO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3INO FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3ino]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_anthracis Bacillus anthracis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3INO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3INO FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">pagA, pag, pXO1-110, BXA0164, GBAA_pXO1_0164 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1392 "Bacillus cereus var. anthracis" (Cohn 1872) Smith et al. 1946])</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ino FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ino OCA], [https://pdbe.org/3ino PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ino RCSB], [https://www.ebi.ac.uk/pdbsum/3ino PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ino ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ino FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ino OCA], [https://pdbe.org/3ino PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ino RCSB], [https://www.ebi.ac.uk/pdbsum/3ino PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ino ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/PAG_BACAN PAG_BACAN]] One of the three proteins composing the anthrax toxin, the agent which infects many mammalian species and that may cause death. PA binds to a receptor (ATR) in sensitive eukaryotic cells, thereby facilitating the translocation of the enzymatic toxin components, edema factor and lethal factor, across the target cell membrane. PA associated with LF causes death when injected, PA associated with EF produces edema. PA induces immunity to infection with anthrax.
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[https://www.uniprot.org/uniprot/PAG_BACAN PAG_BACAN] One of the three proteins composing the anthrax toxin, the agent which infects many mammalian species and that may cause death. PA binds to a receptor (ATR) in sensitive eukaryotic cells, thereby facilitating the translocation of the enzymatic toxin components, edema factor and lethal factor, across the target cell membrane. PA associated with LF causes death when injected, PA associated with EF produces edema. PA induces immunity to infection with anthrax.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bacillus anthracis]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Anbanandam, A]]
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[[Category: Anbanandam A]]
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[[Category: Bann, J G]]
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[[Category: Bann JG]]
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[[Category: El-Chami, R]]
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[[Category: El-Chami R]]
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[[Category: Lovell, S]]
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[[Category: Lovell S]]
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[[Category: Williams, A S]]
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[[Category: Williams AS]]
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[[Category: Anthrax]]
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[[Category: Calcium]]
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[[Category: Cleavage on pair of basic residue]]
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[[Category: Domain 4]]
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[[Category: Immune system]]
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[[Category: Metal-binding]]
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[[Category: Plasmid]]
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[[Category: Protective antigen]]
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[[Category: Secreted]]
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[[Category: Toxin]]
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[[Category: Virulence]]
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Current revision

1.95A Resolution Structure of Protective Antigen Domain 4

PDB ID 3ino

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