Thrombin 3D Structures
From Proteopedia
(Difference between revisions)
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*'''Thrombin''' | *'''Thrombin''' | ||
- | **[[ | + | **[[3gic]], [[3r3g]] - hThr HC + LC - human<br /> |
- | **[[ | + | **[[2od3]], [[3jz1]], [[3jz2]], [[6pxj]], [[6pxq]] - hThr HC + LC (mutant) <br /> |
**[[7sr9]] - hThr HC (mutant) + LC (mutant)<br /> | **[[7sr9]] - hThr HC (mutant) + LC (mutant)<br /> | ||
- | **[[ | + | **[[1jou]], [[1sg8]], [[1sgi]], [[2a0q]], [[3ee0]], [[3qgn]], [[4rkj]], [[5jdu]], [[6pxq]], [[6pxj]], - hThr HC (mutant) + LC<br /> |
**[[2hnt]]– hThr-γ HC + LC<br /> | **[[2hnt]]– hThr-γ HC + LC<br /> | ||
**[[3pmb]] - bThr HC + LC – bovine<br /> | **[[3pmb]] - bThr HC + LC – bovine<br /> | ||
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*Thrombin complexes with small molecule | *Thrombin complexes with small molecule | ||
- | **[[ | + | **[[1abj]], [[1bhx]], [[1ppb]], [[6z48]], [[8ase]] - hThr HC + LC + inhibitor<br /> |
**[[4rn6]] - hThr HC (mutant) + inhibitor<br /> | **[[4rn6]] - hThr HC (mutant) + inhibitor<br /> | ||
**[[3dd2]] - hThr HC + LC + RNA<br /> | **[[3dd2]] - hThr HC + LC + RNA<br /> | ||
- | **[[1hao]], [[1hap]], [[1hut]] - hThr HC + LC + | + | **[[1hao]], [[1hap]], [[1hut]], [[3qlp]], [[4dih]], [[4lz1]], 4lz4]], [[6z8w]], [[6z8x]], [[7ntu]], [[7zkl]], [[7zkm]], [[7zkn]], [[7zko]], [[8bw5]] - hThr HC + LC + aptamer<br /> |
**[[3bf6]] - hThr HC + LC + suramin<br /> | **[[3bf6]] - hThr HC + LC + suramin<br /> | ||
**[[1xmn]] - hThr HC + LC + heparin<br /> | **[[1xmn]] - hThr HC + LC + heparin<br /> | ||
**[[2h9t]] - hThr HC + LC + suramin + PPACK<BR /> | **[[2h9t]] - hThr HC + LC + suramin + PPACK<BR /> | ||
**[[1z8i]], [[1z8j]] - hThr HC + LC (mutant) + PPACK<BR /> | **[[1z8i]], [[1z8j]] - hThr HC + LC (mutant) + PPACK<BR /> | ||
- | **[[ | + | **[[1b7x]], [[1sfq]], [[1shh]], [[1thp]], [[2thf]], [[4rko]] - hThr HC (mutant) + LC + PPACK<BR /> |
**[[1ook]], [[6v64]] - hThr HC + LC + PPACK<BR /> | **[[1ook]], [[6v64]] - hThr HC + LC + PPACK<BR /> | ||
**[[2hpp]], [[2hpq]] - hThr HC + LC + PThr residues 214-292 + PPACK<BR /> | **[[2hpp]], [[2hpq]] - hThr HC + LC + PThr residues 214-292 + PPACK<BR /> | ||
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**[[1fph]] - hThr HC + LC + fibrinogen peptide<br /> | **[[1fph]] - hThr HC + LC + fibrinogen peptide<br /> | ||
**[[3bv9]] - hThr HC (mutant) + LC + peptide inhibitor<br /> | **[[3bv9]] - hThr HC (mutant) + LC + peptide inhibitor<br /> | ||
- | **[[ | + | **[[1dlt]], [[1eb1]], [[1h8d]], [[1h8i]], [[1hbt]], [[2a2x]], [[3u8t]] - hThr HC + LC + peptide inhibitor<br /> |
- | **[[ | + | **[[1eoj]], [[1eol]], [[1g37]], [[1nrn]], [[1nro]], [[1nrp]], [[1nrq]], [[1nrr]], [[1nrs]] - hThr HC + peptide inhibitor<br /> |
**[[1hlt]] - hThr HC + LC + thrombomodulin peptide<br /> | **[[1hlt]] - hThr HC + LC + thrombomodulin peptide<br /> | ||
**[[4ch2]], [[4ch8]] - hThr HC + LC + platelet glycoprotein IB α chain peptide <br /> | **[[4ch2]], [[4ch8]] - hThr HC + LC + platelet glycoprotein IB α chain peptide <br /> | ||
**[[2ank]], [[3po1]] - hThr HC + LC + peptide + inhibitor<br /> | **[[2ank]], [[3po1]] - hThr HC + LC + peptide + inhibitor<br /> | ||
**[[1dlk]] - bThr HC + LC + peptide inhibitor<br /> | **[[1dlk]] - bThr HC + LC + peptide inhibitor<br /> | ||
- | **[[ | + | **[[1bbr]], [[1ycp]] – bThr-ε HC + LC + fibrinogen peptide<br /> |
**[[1ucy]] - bThr HC + LC + fibrinogen peptide<br /> | **[[1ucy]] - bThr HC + LC + fibrinogen peptide<br /> | ||
**[[3hki]] - mThr HC (mutant) + LC + proteinase-activated receptor 1 peptide<br /> | **[[3hki]] - mThr HC (mutant) + LC + proteinase-activated receptor 1 peptide<br /> | ||
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*Thrombin complexes containing hirudin | *Thrombin complexes containing hirudin | ||
- | **[[ | + | **[[1a3b]], [[1a3e]], [[1ype]], [[1a46]], [[1a4w]], [[1a5g]], [[1a61]], [[1ad8]], [[1ae8]], [[1afe]], [[1aht]], [[1ai8]], [[1aix]], [[1awf]], [[1awh]], [[1ay6]], [[1b5g]], [[1ba8]], [[1bb0]], [[1bcu]], [[1bmm]], [[1bmn]], [[1c1u]], [[1c1v]], [[1c1w]], [[1c4u]], [[1c4v]], [[1c4y]], [[1c5n]], [[1c5o]], [[1ca8]], [[1d3d]], [[1d3p]], [[1d3q]], [[1d3t]], [[1d4p]], [[1fpc]], [[1ghv]], [[1ghw]], [[1ghx]], [[1ghy]], [[1qj1]], [[1gj4]], [[1gj5]], [[1qj6]], [[1qj7]], [[1kts]], [[1ktt]], [[1lhc]], [[1lhd]], [[1lhe]], [[1lhf]], [[1lhg]], [[1mu6]], [[1mu8]], [[1mue]], [[1nzq]], [[1o0d]], [[1o2g]], [[1oyt]], ,[[1qhr]], [[1qur]], [[1riw]], [[1tbz]], [[1uma]], [[1vzq]], [[1w7g]], [[1way]], [[1wbg]], [[1ypg]], [[1ypj]], [[1ypk]], [[1ypl]], [[1ypm]], [[2anm]], [[2bdy]], [[2bvr]], [[2bvs]], [[2bvx]], [[2bxt]], [[2bxu]], [[2c8w]], [[2c8x]], [[2c8y]], [[2c8z]], [[2c90]], [[2c93]], [[2cf8]], [[2cf9]], [[2feq]], [[2fes]], [[2gde]], [[2jh0]], [[2jh5]], [[2jh6]], [[2pks]], [[2r2m]], [[2uuj]], [[2uuk]], [[2v3h]], [[2v3o]], [[2w7g]], [[2zc9]], [[2zda]], [[2zdv]], [[2zf0]], [[2zff]], [[2zfp]], [[2zfq]], [[2zfr]], [[2zg0]], [[2zgb]], [[2zgx]], [[2zhe]], [[2zhf]], [[2zhq]], [[2zhw]], [[2zi2]], [[2ziq]], [[[2znk]], [2zo3]], [[3biu]], [[3biv]], [[3c27]], [[3d49]], [[3da9]], [[3dhk]], [[3dt0]], [[3dux]], [[3egk]], [[3eq0]], [[3ldx]], [[3p17]], [[3qto]], [[3qtv]], [[3qwc]], [[3qx5]], [[3rlw]], [[3rly]], [[3rm0]], [[3rm2]], [[3rml]], [[3rmm]], [[3rmn]], [[3rmo]], [[3si3]], [[3si4]], [[3sha]], [[3shc]], [[3sv2]], [[3t5f]], [[3u98]], [[3u9a]], [[3uwj]], [[4e7r]], [[4loy]], [[6eo8]], [[6eo9]], [[6gbw]], [[6zgo]] - hThr HC + LC + hirudin peptide + inhibitor<br /> |
- | + | ||
**[[7ac9]] – hThr HC + LC + hirudin peptide + Arg<br /> | **[[7ac9]] – hThr HC + LC + hirudin peptide + Arg<br /> | ||
- | **[[ | + | **[[1d6w]], [[1d9i]], [[1doj]], [[1dwb]], [[1dwc]], [[1dwd]], [[1dwe]], [[1qbv]], [[1tmu]], [[1nm6]], [[1nt1]], [[1sl3]], [[1ta2]], [[1ta6]], [[1xm1]], [[1z71]], [[1zgi]], [[1zgv]], [[1zrb]], [[4baq]], [[4bao]], [[4ban]], [[4ud9]], [[4udw]], [[4ue7]], [[4ueh]], [[4ufd]], [[4ufe]], [[4uff]], [[4ufg]], [[4yes]], [[5a2m]], [[5af9]], - hThr HC + hirudin peptide + inhibitor<br /> |
- | **[[ | + | **[[1a2c]], [[1hdt]], [[1ny2]], [[1tmt]], [[1tmb]], [[1tom]], [[3u8o]], [[3u8r]], [[7kme]], [[8kme]] - hThr HC + LC + hirudin peptide + peptide inhibitor<br /> |
**[[3hat]] - hThr HC + LC + hirudin peptide + fibrinogen peptide<br /> | **[[3hat]] - hThr HC + LC + hirudin peptide + fibrinogen peptide<br /> | ||
- | **[[ | + | **[[1abi]], [[1c5l]], [[1hgt]], [[1hxe]], [[1hxf]], [[1ihs]], [[1iht]], [[1no9]], [[1thr]], [[1ths]], [[1vr1]], [[2hgt]], [[2pw8]], [[2uuf]], [[3htc]], [[3utu]], [[4ayv]], [[4ayy]], [[4az2]], [[4htc]], [[4thn]], [[5gds]] - hThr HC + LC + hirudin peptide<br /> |
**[[3vxe]], [[3vxf]] - hThr HC + LC + bivalirudin peptide<br /> | **[[3vxe]], [[3vxf]] - hThr HC + LC + bivalirudin peptide<br /> | ||
**[[4mlf]] - hThr HC (mutant) + LC + hirudin peptide<br /> | **[[4mlf]] - hThr HC (mutant) + LC + hirudin peptide<br /> | ||
- | **[[ | + | **[[5mls]], [[5mjt]], [[5mm6]] - hThr HC (mutant) + LC + hirudin peptide + inhibitor<br /> |
- | **[[ | + | **[[1hrt]], [[1vit]] - bThr HC + LC + hirudin peptide<br /> |
*Thrombin complex with protein | *Thrombin complex with protein | ||
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**[[3pmh]] - hThr HC + LC + platelet glycoprotein IB α chain<br /> | **[[3pmh]] - hThr HC + LC + platelet glycoprotein IB α chain<br /> | ||
**[[3b23]] - hThr HC + LC + variegin<br /> | **[[3b23]] - hThr HC + LC + variegin<br /> | ||
- | **[[ | + | **[[6tkh]], [[6tki]], [[6tkj]] - hThr HC + LC + tsetse Thr inhibitor<br /> |
**[[5e8e]] - hThr HC + LC + antibody<br /> | **[[5e8e]] - hThr HC + LC + antibody<br /> | ||
- | **[[ | + | **[[1nu7]], [[2a1d]] – bThr HC + LC + staphylocoagulase<br /> |
**[[1avg]] - bThr HC + LC + triabin<br /> | **[[1avg]] - bThr HC + LC + triabin<br /> | ||
**[[1bth]] - bThr HC (mutant) + LC (mutant) + BPTI<br /> | **[[1bth]] - bThr HC (mutant) + LC (mutant) + BPTI<br /> | ||
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*'''Prothrombin''' | *'''Prothrombin''' | ||
- | **[[ | + | **[[2afq]], [[3e6p]], [[3u69]], [[6v5t]] - hPThr HC + LC<br /> |
**[[3s7h]], [[3s7k]], [[6p9u]] – hPThr HC + LC (mutant) <br /> | **[[3s7h]], [[3s7k]], [[6p9u]] – hPThr HC + LC (mutant) <br /> | ||
- | **[[ | + | **[[1rd3]], [[1tq0]], [[2gp9]], [[2pgb]], [[3bei]], [[4h6s]], [[4h6t]], [[4hzh]], [[6bjr]], [[6c2w]] - hPThr HC (mutant) + LC<br /> |
**[[1mh0]], [[4nzq]], [[4o03]] - hPThr HC (mutant) <br /> | **[[1mh0]], [[4nzq]], [[4o03]] - hPThr HC (mutant) <br /> | ||
- | **[[1nl1]], [[1nl2]], [[ | + | **[[1nl1]], [[1nl2]], [[2pf1]], [[2pf2]], [[2spt]] – bPThr residues 1-156 |
*Prothrombin complexes | *Prothrombin complexes | ||
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**[[6cym]] - hPThr HC + LC + inhibitor<br /> | **[[6cym]] - hPThr HC + LC + inhibitor<br /> | ||
**[[3qdz]] – hPThr HC (mutant) + LC + proteinase-activated receptor 4 peptide<br /> | **[[3qdz]] – hPThr HC (mutant) + LC + proteinase-activated receptor 4 peptide<br /> | ||
- | **[[ | + | **[[3bef]], [[3lu9]] - hPThr HC + LC (mutant) + proteinase-activated receptor 1 peptide<br /> |
**[[1sr5]] - hPThr HC + LC + antithrombin III<br /> | **[[1sr5]] - hPThr HC + LC + antithrombin III<br /> | ||
**[[3k65]] - hPThr HC residues 315-622 (mutant) + LC residues 199-314<br /> | **[[3k65]] - hPThr HC residues 315-622 (mutant) + LC residues 199-314<br /> | ||
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**[[1jwt]], [[3c1k]] - hPThr HC + inhibitor<br /> | **[[1jwt]], [[3c1k]] - hPThr HC + inhibitor<br /> | ||
**[[4hfp]] - hPThr HC (mutant) + LC + inhibitor<br /> | **[[4hfp]] - hPThr HC (mutant) + LC + inhibitor<br /> | ||
- | **[[ | + | **[[1tq7]], [[2pgq]] - hPThr HC (mutant) + LC + PPACK<BR /> |
**[[6gwe]], [[6t7h]] - hPThr HC + LC + macrocycle<br /> | **[[6gwe]], [[6t7h]] - hPThr HC + LC + macrocycle<br /> | ||
- | **[[ | + | **[[1g30]], [[1g32]], [[1k21]], [[1k22]], [[1o5g]], [[1sb1]], [[1t4u]], [[1t4v]], [[2cno]], [[3tu7]], [[4lxb]], [[5jfd]], [[5jzy]], [[5lce]], [[6eo8]], [[6eo9]] [[6fjt]], [[6gbw]], [[6hsx]], [[6i51]], [[6rot]], [[6t3m]], [[6t3q]], [[6t4a]], [[6t52]], [[6t53]], [[6t54]], [[6t55]], [[6t56]], [[6t57]], [[6t89]], [[6t8a]], [[6tdt]], [[6y02]], [[6y9h]], [[6yb6]], [[6yhg]], [[6yhj]], [[6ymp]], [[6yn3]], [[6yqv]], [[6ysj]], [[6ysx]], [[6zug]], [[6zuh]], [[6zun]], [[6zuu]], [[6zuw]], [[6zux]], [[6zv7]], [[6zv8]] - hPThr HC + LC + hirudin peptide + inhibitor<br /> |
**[[4ax9]] - hPThr HC + LC + hirudin peptide<br /> | **[[4ax9]] - hPThr HC + LC + hirudin peptide<br /> | ||
**[[1twx]] - hPThr HC (mutant) + LC + hirudin peptide<br /> | **[[1twx]] - hPThr HC (mutant) + LC + hirudin peptide<br /> | ||
**[[2hwl]] - hPThr HC (mutant) + LC + fibrinogen γ’ peptide<br /> | **[[2hwl]] - hPThr HC (mutant) + LC + fibrinogen γ’ peptide<br /> | ||
- | **[[ | + | **[[4dii]], [[4i7y]], [[5ew1]], [[5ew2]], [[5cmx]], [[6eo6]], [[6eo7]], [[6evv]], [[6gn7]], [[6z8v]] - hPThr HC + LC + aptamer<br /> |
**[[5do4]] - hPThr HC + LC + RNA<br /> | **[[5do4]] - hPThr HC + LC + RNA<br /> | ||
- | **[[7a0e]], [[7a0f]] - bPThr + hirudin peptide<br /> | + | **[[7a0d]], [[7a0e]], [[7a0f]] - bPThr + hirudin peptide<br /> |
*Prothrombin complex with protein | *Prothrombin complex with protein | ||
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*'''Meizothrombin''' | *'''Meizothrombin''' | ||
- | **[[1a0h]] | + | **[[1a0h]] – bMThr |
+ | |||
+ | *'''Saxthrombin''' | ||
+ | |||
+ | **[[3s69]] – Thr – ''Gloydis saxatilis''<br /> | ||
}} | }} | ||
[[Category:Topic Page]] | [[Category:Topic Page]] |
Revision as of 11:00, 24 December 2023
3D Structures of thrombin
Updated on 24-December-2023 - For a general description of the protein see Thrombin