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5vcn

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Current revision (13:46, 4 October 2023) (edit) (undo)
 
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<StructureSection load='5vcn' size='340' side='right'caption='[[5vcn]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
<StructureSection load='5vcn' size='340' side='right'caption='[[5vcn]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5vcn]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Dermatophagoides_pteronyssinus Dermatophagoides pteronyssinus] and [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=4pp1 4pp1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5VCN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5VCN FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5vcn]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Dermatophagoides_pteronyssinus Dermatophagoides pteronyssinus] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=4pp1 4pp1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5VCN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5VCN FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3rvw|3rvw]], [[3rvv|3rvv]], [[3rvx|3rvx]], [[4poz|4poz]], [[4pp2|4pp2]], [[5vco|5vco]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5vcn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5vcn OCA], [https://pdbe.org/5vcn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5vcn RCSB], [https://www.ebi.ac.uk/pdbsum/5vcn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5vcn ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5vcn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5vcn OCA], [https://pdbe.org/5vcn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5vcn RCSB], [https://www.ebi.ac.uk/pdbsum/5vcn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5vcn ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PEPT1_DERPT PEPT1_DERPT] Thiol protease, with a preference for substrates with a large hydrophobic side chain in the P2 position, or with basic residues.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 5vcn" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5vcn" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Monoclonal Antibodies 3D structures|Monoclonal Antibodies 3D structures]]
== References ==
== References ==
<references/>
<references/>
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[[Category: Dermatophagoides pteronyssinus]]
[[Category: Dermatophagoides pteronyssinus]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Lk3 transgenic mice]]
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[[Category: Mus musculus]]
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[[Category: Chapman, M D]]
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[[Category: Chapman MD]]
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[[Category: Chruszcz, M]]
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[[Category: Chruszcz M]]
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[[Category: Glesner, J]]
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[[Category: Glesner J]]
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[[Category: Majorek, K A]]
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[[Category: Majorek KA]]
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[[Category: Minor, W]]
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[[Category: Minor W]]
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[[Category: Offermann, L R]]
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[[Category: Offermann LR]]
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[[Category: Osinski, S]]
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[[Category: Osinski S]]
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[[Category: Osinski, T]]
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[[Category: Osinski T]]
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[[Category: Pomes, A]]
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[[Category: Pomes A]]
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[[Category: Vailes, L D]]
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[[Category: Vailes LD]]
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[[Category: Allergen]]
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[[Category: Antibody]]
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[[Category: Immune system]]
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Current revision

THE CRYSTAL STRUCTURE OF DER P 1 ALLERGEN COMPLEXED WITH FAB FRAGMENT OF MAB 5H8

PDB ID 5vcn

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