This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


2yfv

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (10:51, 20 December 2023) (edit) (undo)
 
Line 3: Line 3:
<StructureSection load='2yfv' size='340' side='right'caption='[[2yfv]], [[Resolution|resolution]] 2.32&Aring;' scene=''>
<StructureSection load='2yfv' size='340' side='right'caption='[[2yfv]], [[Resolution|resolution]] 2.32&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[2yfv]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Candida_sphaerica Candida sphaerica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YFV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2YFV FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[2yfv]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Kluyveromyces_lactis_NRRL_Y-1140 Kluyveromyces lactis NRRL Y-1140]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YFV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2YFV FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.32&#8491;</td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2yfw|2yfw]]</div></td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2yfv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yfv OCA], [https://pdbe.org/2yfv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2yfv RCSB], [https://www.ebi.ac.uk/pdbsum/2yfv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2yfv ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2yfv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yfv OCA], [https://pdbe.org/2yfv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2yfv RCSB], [https://www.ebi.ac.uk/pdbsum/2yfv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2yfv ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
-
[[https://www.uniprot.org/uniprot/CENPA_KLULA CENPA_KLULA]] Histone H3-like variant which exclusively replaces conventional H3 in the nucleosome core of centromeric chromatin at the inner plate of the kinetochore. Required for recruitment and assembly of kinetochore proteins, mitotic progression and chromosome segregation. May serve as an epigenetic mark that propagates centromere identity through replication and cell division (By similarity). [[https://www.uniprot.org/uniprot/Q6CMU6_KLULA Q6CMU6_KLULA]] Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling (By similarity).[SAAS:SAAS00202799]
+
[https://www.uniprot.org/uniprot/CENPA_KLULA CENPA_KLULA] Histone H3-like variant which exclusively replaces conventional H3 in the nucleosome core of centromeric chromatin at the inner plate of the kinetochore. Required for recruitment and assembly of kinetochore proteins, mitotic progression and chromosome segregation. May serve as an epigenetic mark that propagates centromere identity through replication and cell division (By similarity).
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 26: Line 26:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Candida sphaerica]]
+
[[Category: Kluyveromyces lactis NRRL Y-1140]]
[[Category: Large Structures]]
[[Category: Large Structures]]
-
[[Category: Cho, U S]]
+
[[Category: Cho US]]
-
[[Category: Harrison, S C]]
+
[[Category: Harrison SC]]
-
[[Category: Budding yeast]]
+
-
[[Category: Cell cycle]]
+
-
[[Category: Centromere]]
+
-
[[Category: Histone chaperone]]
+
-
[[Category: Kinetochore]]
+

Current revision

The heterotrimeric complex of Kluyveromyces lactis Scm3, Cse4 and H4

PDB ID 2yfv

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2yfv"
Personal tools