2ygp

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Current revision (14:04, 1 February 2024) (edit) (undo)
 
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<StructureSection load='2ygp' size='340' side='right'caption='[[2ygp]], [[Resolution|resolution]] 2.22&Aring;' scene=''>
<StructureSection load='2ygp' size='340' side='right'caption='[[2ygp]], [[Resolution|resolution]] 2.22&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2ygp]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YGP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2YGP FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2ygp]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YGP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2YGP FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PCF:1,2-DIACYL-SN-GLYCERO-3-PHOSHOCHOLINE'>PCF</scene>, <scene name='pdbligand=SPD:SPERMIDINE'>SPD</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.222&#8491;</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MLY:N-DIMETHYL-LYSINE'>MLY</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MLY:N-DIMETHYL-LYSINE'>MLY</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PCF:1,2-DIACYL-SN-GLYCERO-3-PHOSHOCHOLINE'>PCF</scene>, <scene name='pdbligand=SPD:SPERMIDINE'>SPD</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2ygq|2ygq]], [[2ygo|2ygo]], [[2ygn|2ygn]]</div></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ygp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ygp OCA], [https://pdbe.org/2ygp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ygp RCSB], [https://www.ebi.ac.uk/pdbsum/2ygp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ygp ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ygp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ygp OCA], [https://pdbe.org/2ygp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ygp RCSB], [https://www.ebi.ac.uk/pdbsum/2ygp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ygp ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/WIF1_HUMAN WIF1_HUMAN]] Binds to WNT proteins and inhibits their activities. May be involved in mesoderm segmentation.
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[https://www.uniprot.org/uniprot/WIF1_HUMAN WIF1_HUMAN] Binds to WNT proteins and inhibits their activities. May be involved in mesoderm segmentation.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Aricescu, A R]]
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[[Category: Aricescu AR]]
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[[Category: Jones, E Y]]
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[[Category: Jones EY]]
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[[Category: Lu, W]]
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[[Category: Lu W]]
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[[Category: Malinauskas, T]]
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[[Category: Malinauskas T]]
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[[Category: Siebold, C]]
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[[Category: Siebold C]]
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[[Category: Cancer]]
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[[Category: Glycosaminoglycan]]
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[[Category: Morphogen]]
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[[Category: Signaling protein]]
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[[Category: Wnt antagonist]]
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[[Category: Wnt signaling pathway]]
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Current revision

WIF domain-EGF-like domain 1 Met77Trp of human Wnt inhibitory factor 1 in complex with 1,2-dipalmitoylphosphatidylcholine

PDB ID 2ygp

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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