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2yk4

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Current revision (10:54, 20 December 2023) (edit) (undo)
 
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<StructureSection load='2yk4' size='340' side='right'caption='[[2yk4]], [[Resolution|resolution]] 1.94&Aring;' scene=''>
<StructureSection load='2yk4' size='340' side='right'caption='[[2yk4]], [[Resolution|resolution]] 1.94&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2yk4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Neimi Neimi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YK4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2YK4 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2yk4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Neisseria_meningitidis_serogroup_B Neisseria meningitidis serogroup B]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YK4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2YK4 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=EGC:2-(2-{2-[2-(2-{2-[2-(2-{2-[4-(1,1,3,3-TETRAMETHYL-BUTYL)-PHENOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL'>EGC</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.94&#8491;</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=EGC:2-(2-{2-[2-(2-{2-[2-(2-{2-[4-(1,1,3,3-TETRAMETHYL-BUTYL)-PHENOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL'>EGC</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2yk5|2yk5]], [[2yk7|2yk7]], [[2yk6|2yk6]]</div></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2yk4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yk4 OCA], [https://pdbe.org/2yk4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2yk4 RCSB], [https://www.ebi.ac.uk/pdbsum/2yk4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2yk4 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2yk4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yk4 OCA], [https://pdbe.org/2yk4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2yk4 RCSB], [https://www.ebi.ac.uk/pdbsum/2yk4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2yk4 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/LST_NEIMB LST_NEIMB]] Transfers sialic acid from the substrate CMP-sialic acid donor to the terminal beta-D-galactosyl-1,4-acetyl-beta-D-glucosamine on the lacto-N-neotetraose branch of the lipooligosaccharide.
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[https://www.uniprot.org/uniprot/LST_NEIMB LST_NEIMB] Transfers sialic acid from the substrate CMP-sialic acid donor to the terminal beta-D-galactosyl-1,4-acetyl-beta-D-glucosamine on the lacto-N-neotetraose branch of the lipooligosaccharide.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Neimi]]
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[[Category: Neisseria meningitidis serogroup B]]
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[[Category: Chiu, C P.C]]
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[[Category: Chiu CPC]]
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[[Category: Lameignere, E]]
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[[Category: Lameignere E]]
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[[Category: Lin, L Y.C]]
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[[Category: Lin LYC]]
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[[Category: Rakic, B]]
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[[Category: Rakic B]]
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[[Category: Strynadka, N C.J]]
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[[Category: Strynadka NCJ]]
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[[Category: Wakarchuk, W W]]
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[[Category: Wakarchuk WW]]
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[[Category: Withers, S G]]
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[[Category: Withers SG]]
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[[Category: Transferase]]
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Current revision

Structure of Neisseria LOS-specific sialyltransferase (NST).

PDB ID 2yk4

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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