1h07

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:1h07.gif|left|200px]]
+
{{Seed}}
 +
[[Image:1h07.png|left|200px]]
<!--
<!--
Line 9: Line 10:
{{STRUCTURE_1h07| PDB=1h07 | SCENE= }}
{{STRUCTURE_1h07| PDB=1h07 | SCENE= }}
-
'''CDK2 IN COMPLEX WITH A DISUBSTITUTED 4, 6-BIS ANILINO PYRIMIDINE CDK4 INHIBITOR'''
+
===CDK2 IN COMPLEX WITH A DISUBSTITUTED 4, 6-BIS ANILINO PYRIMIDINE CDK4 INHIBITOR===
-
==Overview==
+
<!--
-
Using a high-throughput screening campaign, we identified the 4,6-bis anilino pyrimidines as inhibitors of the cyclin-dependent kinase, CDK4. Herein we describe the further chemical modification and use of X-ray crystallography to develop potent and selective in vitro inhibitors of CDK4.
+
The line below this paragraph, {{ABSTRACT_PUBMED_12941311}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 12941311 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_12941311}}
==About this Structure==
==About this Structure==
Line 35: Line 39:
[[Category: Tucker, J A.]]
[[Category: Tucker, J A.]]
[[Category: Serine/threonine-protein kinase,mitosis,transferase]]
[[Category: Serine/threonine-protein kinase,mitosis,transferase]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 18:14:57 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 06:24:14 2008''

Revision as of 03:24, 1 July 2008

Image:1h07.png

Template:STRUCTURE 1h07

CDK2 IN COMPLEX WITH A DISUBSTITUTED 4, 6-BIS ANILINO PYRIMIDINE CDK4 INHIBITOR

Template:ABSTRACT PUBMED 12941311

About this Structure

1H07 is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Cyclin-dependent kinase 4 inhibitors as a treatment for cancer. Part 1: identification and optimisation of substituted 4,6-bis anilino pyrimidines., Beattie JF, Breault GA, Ellston RP, Green S, Jewsbury PJ, Midgley CJ, Naven RT, Minshull CA, Pauptit RA, Tucker JA, Pease JE, Bioorg Med Chem Lett. 2003 Sep 15;13(18):2955-60. PMID:12941311

Page seeded by OCA on Tue Jul 1 06:24:14 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1h07"
Personal tools