Autocrine signaling
From Proteopedia
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Autocrine signaling is a form of cell signaling in which a cell secretes a hormone or chemical messenger (called the autocrine agent) that binds to autocrine receptors on that same cell, leading to changes in the cell. | Autocrine signaling is a form of cell signaling in which a cell secretes a hormone or chemical messenger (called the autocrine agent) that binds to autocrine receptors on that same cell, leading to changes in the cell. | ||
| - | An example of an autocrine agent is the cytokine interleukin-1 in monocytes (see [[Interleukin]]). When interleukin-1 is produced in response to external stimuli, it can bind to cell-surface receptors on the same cell that produced it (see [[Interleukin receptors]]). | + | An example of an autocrine agent is the cytokine interleukin-1 in monocytes (see [[Interleukin]]). When interleukin-1 is produced in response to external stimuli, it can bind to cell-surface receptors on the same cell that produced it (see [[Interleukin receptors]]). |
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| + | Normally, the [[Wnt signaling pathway]] leads to stabilization of β-catenin through inactivation of a protein complex containing the tumor suppressors APC and Axin. | ||
</StructureSection> | </StructureSection> | ||
== References == | == References == | ||
<references/> | <references/> | ||
Revision as of 13:45, 2 May 2022
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