7x68
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
==CYS179 and CYS504 of CRMP2 were covalently binded by a Sesquiterpene lactone== | ==CYS179 and CYS504 of CRMP2 were covalently binded by a Sesquiterpene lactone== | ||
| - | <StructureSection load='7x68' size='340' side='right'caption='[[7x68]]' scene=''> | + | <StructureSection load='7x68' size='340' side='right'caption='[[7x68]], [[Resolution|resolution]] 1.80Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7X68 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7X68 FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[7x68]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7X68 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7X68 FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7x68 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7x68 OCA], [https://pdbe.org/7x68 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7x68 RCSB], [https://www.ebi.ac.uk/pdbsum/7x68 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7x68 ProSAT]</span></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8Å</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BX0:(3aR,5S,8R,8aR,9aR)-5,8a-dimethyl-3-methylidene-8-oxidanyl-5,6,7,8,9,9a-hexahydro-3aH-benzo[f][1]benzofuran-2-one'>BX0</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7x68 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7x68 OCA], [https://pdbe.org/7x68 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7x68 RCSB], [https://www.ebi.ac.uk/pdbsum/7x68 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7x68 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/DPYL2_HUMAN DPYL2_HUMAN] Plays a role in neuronal development and polarity, as well as in axon growth and guidance, neuronal growth cone collapse and cell migration. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton (By similarity). Plays a role in neuron projection morphogenesis.<ref>PMID:11477421</ref> <ref>PMID:15466863</ref> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Ma YF]] | [[Category: Ma YF]] | ||
[[Category: Zhang J]] | [[Category: Zhang J]] | ||
[[Category: Zhang SD]] | [[Category: Zhang SD]] | ||
Revision as of 17:48, 29 November 2023
CYS179 and CYS504 of CRMP2 were covalently binded by a Sesquiterpene lactone
| |||||||||||
