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7nex

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Current revision (12:34, 1 February 2024) (edit) (undo)
 
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<StructureSection load='7nex' size='340' side='right'caption='[[7nex]], [[Resolution|resolution]] 1.81&Aring;' scene=''>
<StructureSection load='7nex' size='340' side='right'caption='[[7nex]], [[Resolution|resolution]] 1.81&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[7nex]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7NEX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7NEX FirstGlance]. <br>
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<table><tr><td colspan='2'>[[7nex]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Schistosoma_mansoni Schistosoma mansoni]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7NEX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7NEX FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=8JS:4-{[(4-fluorophenyl)carbamothioyl]amino}benzene-1-sulfonamide'>8JS</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.81&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Carbonate_dehydratase Carbonate dehydratase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.1 4.2.1.1] </span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=8JS:4-{[(4-fluorophenyl)carbamothioyl]amino}benzene-1-sulfonamide'>8JS</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7nex FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7nex OCA], [https://pdbe.org/7nex PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7nex RCSB], [https://www.ebi.ac.uk/pdbsum/7nex PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7nex ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7nex FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7nex OCA], [https://pdbe.org/7nex PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7nex RCSB], [https://www.ebi.ac.uk/pdbsum/7nex PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7nex ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/A0A3Q0KSG2_SCHMA A0A3Q0KSG2_SCHMA]] Reversible hydration of carbon dioxide.[RuleBase:RU367011]
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[https://www.uniprot.org/uniprot/A0A3Q0KSG2_SCHMA A0A3Q0KSG2_SCHMA] Reversible hydration of carbon dioxide.[RuleBase:RU367011]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 7nex" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 7nex" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Carbonic anhydrase 3D structures|Carbonic anhydrase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Carbonate dehydratase]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Angeli, A]]
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[[Category: Schistosoma mansoni]]
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[[Category: Ferraroni, M]]
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[[Category: Angeli A]]
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[[Category: Supuran, C T]]
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[[Category: Ferraroni M]]
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[[Category: Lyase]]
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[[Category: Supuran CT]]

Current revision

Crystal structure of alpha Carbonic anhydrase from Schistosoma mansoni bound to 1-(4-fluorophenyl)-3-(4-sulfamoylph enyl)thiourea

PDB ID 7nex

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