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3mjx

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<StructureSection load='3mjx' size='340' side='right'caption='[[3mjx]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
<StructureSection load='3mjx' size='340' side='right'caption='[[3mjx]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3mjx]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Dicdi Dicdi] and [https://en.wikipedia.org/wiki/Dictyostelium_discoideum Dictyostelium discoideum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MJX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3MJX FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3mjx]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Dictyostelium_discoideum Dictyostelium discoideum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MJX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3MJX FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AD9:ADP+METAVANADATE'>AD9</scene>, <scene name='pdbligand=BIT:(-)-1-PHENYL-1,2,3,4-TETRAHYDRO-4-HYDROXYPYRROLO[2,3-B]-7-METHYLQUINOLIN-4-ONE'>BIT</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2jhr|2jhr]], [[2jj9|2jj9]], [[3bz7|3bz7]], [[3bz8|3bz8]], [[3bz9|3bz9]], [[1yv3|1yv3]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AD9:ADP+METAVANADATE'>AD9</scene>, <scene name='pdbligand=BIT:(-)-1-PHENYL-1,2,3,4-TETRAHYDRO-4-HYDROXYPYRROLO[2,3-B]-7-METHYLQUINOLIN-4-ONE'>BIT</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">mhcA, DDB_G0286355 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=44689 DICDI])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3mjx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mjx OCA], [https://pdbe.org/3mjx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3mjx RCSB], [https://www.ebi.ac.uk/pdbsum/3mjx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3mjx ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3mjx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mjx OCA], [https://pdbe.org/3mjx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3mjx RCSB], [https://www.ebi.ac.uk/pdbsum/3mjx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3mjx ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/MYS2_DICDI MYS2_DICDI]] Myosin is a protein that binds to actin and has ATPase activity that is activated by actin.
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[https://www.uniprot.org/uniprot/MYS2_DICDI MYS2_DICDI] Myosin is a protein that binds to actin and has ATPase activity that is activated by actin.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Dicdi]]
 
[[Category: Dictyostelium discoideum]]
[[Category: Dictyostelium discoideum]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Baruch, P]]
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[[Category: Baruch P]]
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[[Category: Bauer, S]]
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[[Category: Bauer S]]
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[[Category: Fedorov, R]]
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[[Category: Fedorov R]]
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[[Category: Manstein, D J]]
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[[Category: Manstein DJ]]
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[[Category: Actin-binding]]
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[[Category: Adp-metavanadate]]
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[[Category: Allosteric]]
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[[Category: Atp-binding]]
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[[Category: Blebbistatin]]
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[[Category: Calmodulin-binding]]
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[[Category: Contractile protein]]
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[[Category: Methylation]]
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[[Category: Motor protein]]
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[[Category: Myosin]]
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[[Category: Nucleotide-binding]]
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[[Category: Phosphoprotein]]
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[[Category: Structural protein]]
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Revision as of 08:54, 6 September 2023

Crystal structure of myosin-2 motor domain in complex with ADP-Metavanadate and blebbistatin

PDB ID 3mjx

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