2vkj

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<StructureSection load='2vkj' size='340' side='right'caption='[[2vkj]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
<StructureSection load='2vkj' size='340' side='right'caption='[[2vkj]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2vkj]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_43589 Atcc 43589]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VKJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2VKJ FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2vkj]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VKJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2VKJ FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.65&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2vko|2vko]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2vkj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vkj OCA], [https://pdbe.org/2vkj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2vkj RCSB], [https://www.ebi.ac.uk/pdbsum/2vkj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2vkj ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2vkj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vkj OCA], [https://pdbe.org/2vkj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2vkj RCSB], [https://www.ebi.ac.uk/pdbsum/2vkj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2vkj ProSAT]</span></td></tr>
</table>
</table>
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<div style="background-color:#fffaf0;">
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== Function ==
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== Publication Abstract from PubMed ==
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[https://www.uniprot.org/uniprot/Q9X1W9_THEMA Q9X1W9_THEMA]
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As a part of the Joint Center for Structural Genomics (JCSG) biological targets, the structures of soluble domains of membrane proteins from Thermotoga maritima were pursued. Here, we report the crystal structure of the soluble domain of TM1634, a putative membrane protein of 128 residues (15.1 kDa) and unknown function. The soluble domain of TM1634 is an alpha-helical dimer that contains a single tetratrico peptide repeat (TPR) motif in each monomer where each motif is similar to that found in Tom20. The overall fold, however, is unique and a DALI search does not identify similar folds beyond the 38-residue TPR motif. Two different putative ligand binding sites, in which PEG200 and Co(2+) were located, were identified using crystallography and NMR, respectively.
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Structure and ligand binding of the soluble domain of a Thermotoga maritima membrane protein of unknown function TM1634.,McCleverty CJ, Columbus L, Kreusch A, Lesley SA Protein Sci. 2008 Mar 27;. PMID:18369189<ref>PMID:18369189</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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<div class="pdbe-citations 2vkj" style="background-color:#fffaf0;"></div>
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== References ==
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<references/>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Atcc 43589]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Columbus, L]]
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[[Category: Thermotoga maritima]]
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[[Category: Structural genomic]]
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[[Category: Columbus L]]
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[[Category: Kreusch, A]]
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[[Category: Kreusch A]]
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[[Category: Lesley, S A]]
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[[Category: Lesley SA]]
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[[Category: McCleverty, C J]]
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[[Category: McCleverty CJ]]
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[[Category: Jcsg]]
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[[Category: Membrane protein]]
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Revision as of 09:57, 14 February 2024

Structure of the soluble domain of the membrane protein TM1634 from Thermotoga maritima

PDB ID 2vkj

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