This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


3ndg

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (09:13, 6 September 2023) (edit) (undo)
 
Line 3: Line 3:
<StructureSection load='3ndg' size='340' side='right'caption='[[3ndg]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
<StructureSection load='3ndg' size='340' side='right'caption='[[3ndg]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[3ndg]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_tuberculosis"_(zopf_1883)_klein_1884 "bacillus tuberculosis" (zopf 1883) klein 1884]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NDG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3NDG FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[3ndg]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NDG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3NDG FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=7EP:(2R,4S)-2-[(1R)-1-{[(2,6-DIMETHOXYPHENYL)CARBONYL]AMINO}-2-OXOETHYL]-5,5-DIMETHYL-1,3-THIAZOLIDINE-4-CARBOXYLIC+ACID'>7EP</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">blaA, blaC, MT2128, MTCY49.07c, Rv2068c ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 "Bacillus tuberculosis" (Zopf 1883) Klein 1884])</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=7EP:(2R,4S)-2-[(1R)-1-{[(2,6-DIMETHOXYPHENYL)CARBONYL]AMINO}-2-OXOETHYL]-5,5-DIMETHYL-1,3-THIAZOLIDINE-4-CARBOXYLIC+ACID'>7EP</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ndg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ndg OCA], [https://pdbe.org/3ndg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ndg RCSB], [https://www.ebi.ac.uk/pdbsum/3ndg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ndg ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ndg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ndg OCA], [https://pdbe.org/3ndg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ndg RCSB], [https://www.ebi.ac.uk/pdbsum/3ndg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ndg ProSAT]</span></td></tr>
</table>
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/BLAC_MYCTU BLAC_MYCTU]
==See Also==
==See Also==
Line 14: Line 15:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Beta-lactamase]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
-
[[Category: Blanchard, J S]]
+
[[Category: Mycobacterium tuberculosis]]
-
[[Category: Tremblay, L W]]
+
[[Category: Blanchard JS]]
-
[[Category: Beta-lactam covalent adduct]]
+
[[Category: Tremblay LW]]
-
[[Category: Hydrolase-antibiotic complex]]
+
-
[[Category: Penicillin binding protein]]
+

Current revision

Crystal Structure of BlaC-E166A covalently bound with Methicillin

PDB ID 3ndg

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools