3noi
From Proteopedia
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<StructureSection load='3noi' size='340' side='right'caption='[[3noi]], [[Resolution|resolution]] 1.84Å' scene=''> | <StructureSection load='3noi' size='340' side='right'caption='[[3noi]], [[Resolution|resolution]] 1.84Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3noi]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[3noi]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NOI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3NOI FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1PG:2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL'>1PG</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.842Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1PG:2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL'>1PG</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr> | |
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3noi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3noi OCA], [https://pdbe.org/3noi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3noi RCSB], [https://www.ebi.ac.uk/pdbsum/3noi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3noi ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3noi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3noi OCA], [https://pdbe.org/3noi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3noi RCSB], [https://www.ebi.ac.uk/pdbsum/3noi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3noi ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | + | [https://www.uniprot.org/uniprot/NCTR3_HUMAN NCTR3_HUMAN] Cytotoxicity-activating receptor that contributes to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis. Engagement of NCR3 by BAG6 also promotes dendritic cell (DC) maturation, both through killing those DCs that did not properly acquire a mature phenotype, and inducing NK cells to release TNFA and IFNG, which promotes DC maturation.<ref>PMID:10562324</ref> <ref>PMID:15784725</ref> <ref>PMID:18852879</ref> | |
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Joyce | + | [[Category: Joyce MG]] |
| - | [[Category: Sun | + | [[Category: Sun PD]] |
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Current revision
Crystal Structure of Natural Killer Cell Cytotoxicity Receptor NKp30 (NCR3)
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