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3o8o

From Proteopedia

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Current revision (09:31, 6 September 2023) (edit) (undo)
 
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<StructureSection load='3o8o' size='340' side='right'caption='[[3o8o]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
<StructureSection load='3o8o' size='340' side='right'caption='[[3o8o]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3o8o]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3O8O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3O8O FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3o8o]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3O8O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3O8O FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=F6P:FRUCTOSE-6-PHOSPHATE'>F6P</scene>, <scene name='pdbligand=FDP:FRUCTOSE-2,6-DIPHOSPHATE'>FDP</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PFK1, YGR240C, G8599 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 ATCC 18824]), PFK2, YMR205C, YM8325.06C ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 ATCC 18824])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=F6P:FRUCTOSE-6-PHOSPHATE'>F6P</scene>, <scene name='pdbligand=FDP:FRUCTOSE-2,6-DIPHOSPHATE'>FDP</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/6-phosphofructokinase 6-phosphofructokinase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.11 2.7.1.11] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3o8o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3o8o OCA], [https://pdbe.org/3o8o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3o8o RCSB], [https://www.ebi.ac.uk/pdbsum/3o8o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3o8o ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3o8o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3o8o OCA], [https://pdbe.org/3o8o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3o8o RCSB], [https://www.ebi.ac.uk/pdbsum/3o8o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3o8o ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/PFKA1_YEAST PFKA1_YEAST]] Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.[HAMAP-Rule:MF_03184]<ref>PMID:11221662</ref> <ref>PMID:147195</ref> <ref>PMID:3000145</ref> <ref>PMID:3007939</ref> <ref>PMID:6211191</ref> <ref>PMID:6219673</ref> <ref>PMID:8132627</ref> <ref>PMID:8663166</ref> [[https://www.uniprot.org/uniprot/PFKA2_YEAST PFKA2_YEAST]] Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.[HAMAP-Rule:MF_03184]<ref>PMID:11221662</ref> <ref>PMID:3000145</ref> <ref>PMID:3007939</ref> <ref>PMID:40590</ref> <ref>PMID:6211191</ref> <ref>PMID:6219673</ref> <ref>PMID:8132627</ref> <ref>PMID:8663166</ref>
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[https://www.uniprot.org/uniprot/PFKA1_YEAST PFKA1_YEAST] Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.[HAMAP-Rule:MF_03184]<ref>PMID:11221662</ref> <ref>PMID:147195</ref> <ref>PMID:3000145</ref> <ref>PMID:3007939</ref> <ref>PMID:6211191</ref> <ref>PMID:6219673</ref> <ref>PMID:8132627</ref> <ref>PMID:8663166</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: 6-phosphofructokinase]]
 
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[[Category: Atcc 18824]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Banaszak, K]]
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[[Category: Saccharomyces cerevisiae]]
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[[Category: Kopperschlager, G]]
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[[Category: Banaszak K]]
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[[Category: Mechin, I]]
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[[Category: Kopperschlager G]]
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[[Category: Rypniewski, W]]
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[[Category: Mechin I]]
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[[Category: Kinase]]
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[[Category: Rypniewski W]]
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[[Category: Transferase]]
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Current revision

Structure of phosphofructokinase from Saccharomyces cerevisiae

PDB ID 3o8o

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