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Transferrin receptor
From Proteopedia
| Line 14: | Line 14: | ||
[[1cx8]] – hTfR ectodomain – human<br /> | [[1cx8]] – hTfR ectodomain – human<br /> | ||
| - | [[6y76]] - hTfR apical domain <br /> | + | [[6y76]], [[8p0z]] - hTfR apical domain <br /> |
[[1de4]] - hTfR ectodomain + hemochromatosis protein + β-2-microglobulin<br /> | [[1de4]] - hTfR ectodomain + hemochromatosis protein + β-2-microglobulin<br /> | ||
[[1suv]], [[6soy]], [[6soz]] - hTfR ectodomain + transferrin<br /> | [[1suv]], [[6soy]], [[6soz]] - hTfR ectodomain + transferrin<br /> | ||
| Line 25: | Line 25: | ||
[[3kas]] - hTfR ectodomain + Machupo virus GP1<br /> | [[3kas]] - hTfR ectodomain + Machupo virus GP1<br /> | ||
[[6wrv]], [[6wrw]], [[6wrx]] - hTfR ectodomain + synthetic protein<br /> | [[6wrv]], [[6wrw]], [[6wrx]] - hTfR ectodomain + synthetic protein<br /> | ||
| + | [[7zqs]] - hTfR + DNA – Cryo EM<br /> | ||
== References == | == References == | ||
<references/> | <references/> | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Current revision
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3D structures of transferrin receptor
Updated on 22-January-2024
Domains – apical 197-378; ectodomain 121-760
1cx8 – hTfR ectodomain – human
6y76, 8p0z - hTfR apical domain
1de4 - hTfR ectodomain + hemochromatosis protein + β-2-microglobulin
1suv, 6soy, 6soz - hTfR ectodomain + transferrin
6okd - hTfR ectodomain + TfR-binding cysteine-dense peptide
6d03, 6d04, 6d05 - hTfR ectodomain + transferrin – Cryo EM
6gsr, 6h5i - hTfR ectodomain + ferritin heavy chain – Cryo EM
6s9j - hTfR ectodomain + PRE-GP-C
3s9l, 3s9m, 3s9n - hTfR ectodomain + transferrin N-lobe
2nsu - hTfR ectodomain in dog retrovirus – Cryo EM
3kas - hTfR ectodomain + Machupo virus GP1
6wrv, 6wrw, 6wrx - hTfR ectodomain + synthetic protein
7zqs - hTfR + DNA – Cryo EM
References
- ↑ Levy JE, Jin O, Fujiwara Y, Kuo F, Andrews NC. Transferrin receptor is necessary for development of erythrocytes and the nervous system. Nat Genet. 1999 Apr;21(4):396-9. PMID:10192390 doi:http://dx.doi.org/10.1038/7727
- ↑ Cazzola M, Beguin Y, Bergamaschi G, Guarnone R, Cerani P, Barella S, Cao A, Galanello R. Soluble transferrin receptor as a potential determinant of iron loading in congenital anaemias due to ineffective erythropoiesis. Br J Haematol. 1999 Sep;106(3):752-5. PMID:10468869

