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Transthyretin 3D structures
From Proteopedia
(Difference between revisions)
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*Transthyretin | *Transthyretin | ||
| - | **[[2pab]], [[1tta]], [[1ttb]], [[1etb]], [[1bmz]], [[1f41]], [[1dvq]], [[1fh2]], [[1qwh]], [[2h4e]], [[2qgb]], [[3cbr]], [[3d7p]], [[3cfm]], [[3i9p]], [[3a4d]], [[3a4e]], [[3a4f]], [[3u2i]], [[3w3b]], [[4mrb]], [[4pvl]], [[4pvn]], [[5k1j]], [[5k1n]], [[5cn3]], [[5cnh]], [[5dwp | + | **[[2pab]], [[1tta]], [[1ttb]], [[1etb]], [[1bmz]], [[1f41]], [[1dvq]], [[1fh2]], [[1qwh]], [[1zcr]], [[1zd6]], [[2h4e]], [[2qgb]], [[3cbr]], [[3d7p]], [[3cfm]], [[3i9p]], [[3a4d]], [[3a4e]], [[3a4f]], [[3ssg]], [[3u2i]], [[3w3b]], [[4mrb]], [[4pvl]], [[4pvn]], [[4tlt]], [[5k1j]], [[5k1n]], [[5cn3]], [[5cnh]], [[5dwp]], [[5lll]], [[5n7c]], [[5n62]], [[5n5q]], [[7q3i]], [[8awi]] – hTTR – human<br /> |
**[[3u2j]], [[4pvm]] – hTTR - neutron<br /> | **[[3u2j]], [[4pvm]] – hTTR - neutron<br /> | ||
| - | **[[1eta]], [[1ttc]], [[1tsh]], [[ | + | **[[1eta]], [[1ttc]], [[1tsh]], [[1bzd]], [[1bze]], [[1fhn]], [[1g1o]], [[1x7s]], [[2qel]], [[2trh]], [[2try]], [[3dgd]], [[3did]], [[3kgs]], [[3tfb]] – hTTR (amyloidogenic mutant)<br /> |
| - | **[[7ob4]] - hTTR – Cryo EM<br /> | + | **[[7ob4]], [[8e7d]] - hTTR – Cryo EM<br /> |
| - | **[[6sdz]] - hTTR (amyloidogenic mutant) – Cryo EM<br /> | + | **[[6sdz]], [[8ade]], [[8e7e]], [[8e7h]], [[8e7i]], [[8e7j]], [[8pke]], [[8pkf]], [[8pkg]], [[8tdn]], [[8tdo]] - hTTR (amyloidogenic mutant) – Cryo EM<br /> |
**[[1ttr]] – hTTR (cardiomyapatic mutant) | **[[1ttr]] – hTTR (cardiomyapatic mutant) | ||
| - | **[[1bz8]], [[5ttr]], [[1f86]], [[1gko]], [[1iii]], [[1iik]], [[1ijn]], [[1sok]], [[1soq]], [[1x7t]], [[2g3x]], [[2g3z]], [[2g4e]], [[2g4g]], [[2noy]], [[3bt0]], [[3cxf]], [[3djr]], [[3djs]], [[3djt]], [[3djz]], [[3dk0]], [[3dk2]], [[3do4]], [[3gps]], [[3grb]], [[3grg]], [[3i9a]], [[3i9i]], [[4mrc]], [[4pwe]], [[5dej]], [[5clx]], [[5clx]], [[5clz]], [[5cm1]], [[4tlu]], [[4tnf]], [[4tng]], [[4tkw]], [[4tl4]], [[4tl5]], [[4tlk]], [[4tls]], [[4tm9]], [[4tne]], [[5llv]], [[5h0z]], [[5h0y]], [[5h0x]], [[5h0w]], [[5h0v]], [[5fw8]], [[5fw7]], [[5fw6]], [[5fo2]], [[5cly]], [[6fzl]], [[6fxu]], [[6fwd]], [[6e71]], [[6e75]], [[6e76]], [[5oq0]], [[5nfw]], [[5nfe]], [[6kgb]] – hTTR (mutant)<br /> | + | **[[1bz8]], [[5ttr]], [[1f86]], [[1gko]], [[1iii]], [[1iik]], [[1ijn]], [[1sok]], [[1soq]], [[1x7t]], [[2g3x]], [[2g3z]], [[2g4e]], [[2g4g]], [[2noy]], [[3bt0]], [[3cxf]], [[3djr]], [[3djs]], [[3djt]], [[3djz]], [[3dk0]], [[3dk2]], [[3do4]], [[3gps]], [[3grb]], [[3grg]], [[3i9a]], [[3i9i]], [[4mrc]], [[4pwe]], [[5dej]], [[5clx]], [[5clx]], [[5clz]], [[5cm1]], [[4tlu]], [[4tnf]], [[4tng]], [[4tkw]], [[4tl4]], [[4tl5]], [[4tlk]], [[4tls]], [[4tm9]], [[4tne]], [[5llv]], [[5h0z]], [[5h0y]], [[5h0x]], [[5h0w]], [[5h0v]], [[5fw8]], [[5fw7]], [[5fw6]], [[5fo2]], [[5cly]], [[6fzl]], [[6fxu]], [[6fwd]], [[6e71]], [[6e75]], [[6e76]], [[5oq0]], [[5nfw]], [[5nfe]], [[6kgb]], [[7tha]], [[7wl6]], [[7y1i]], [[7y6j]], [[8hy4]], [[8i00]], [[8i0o]], [[8t5x]] – hTTR (mutant)<br /> |
**[[2nbp]], [[2nbo]] – hTTR (mutant) – NMR<br /> | **[[2nbp]], [[2nbo]] – hTTR (mutant) – NMR<br /> | ||
| + | **[[7rlk]] – TTR – wallaby<br /> | ||
**[[2qpf]] – TTR - mouse | **[[2qpf]] – TTR - mouse | ||
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**[[4abq]], [[4abv]], [[4abw]], [[4ac2]], [[4ac4]], [[4act]], [[4ank]], [[4abu]] – hTTR + ligand<br /> | **[[4abq]], [[4abv]], [[4abw]], [[4ac2]], [[4ac4]], [[4act]], [[4ank]], [[4abu]] – hTTR + ligand<br /> | ||
**[[4des]], [[4det]], [[4der]], [[4dew]], [[4deu]] – hTTR + flavonoid<br /> | **[[4des]], [[4det]], [[4der]], [[4dew]], [[4deu]] – hTTR + flavonoid<br /> | ||
| + | **[[6u0q]], [[7erh]], [[7q9l]], [[7q9n]], [[7qc5]], [[8dw5]], [[8hej]], [[8w48]] – hTTR + inhibitor<br /> | ||
**[[7erh]] – hTTR + inhibitor<br /> | **[[7erh]] – hTTR + inhibitor<br /> | ||
**[[1u21]], [[3cfn]], [[3cfq]], [[3cft]], [[3hj0]], [[3nee]], [[3neo]], [[3p3r]], [[3p3s]], [[3p3t]], [[3p3u]], [[4ky2]], [[4mas]], [[5e23]], [[5e4a]], [[5e4o]], [[5ezp]], [[5ayt]], [[4ydm]], [[4ydn]], [[4tq8]], [[4tqh]], [[4tqi]], [[4tqp]], [[5jim]], [[5jid]], [[6gr7]], [[6grp]], [[6ep1]], [[5u4g]], [[6tjn]], [[6ti9]] – hTTR + inhibitor<br /> | **[[1u21]], [[3cfn]], [[3cfq]], [[3cft]], [[3hj0]], [[3nee]], [[3neo]], [[3p3r]], [[3p3s]], [[3p3t]], [[3p3u]], [[4ky2]], [[4mas]], [[5e23]], [[5e4a]], [[5e4o]], [[5ezp]], [[5ayt]], [[4ydm]], [[4ydn]], [[4tq8]], [[4tqh]], [[4tqi]], [[4tqp]], [[5jim]], [[5jid]], [[6gr7]], [[6grp]], [[6ep1]], [[5u4g]], [[6tjn]], [[6ti9]] – hTTR + inhibitor<br /> | ||
| - | **[[3nes]], [[3nex]], [[7dt3]], [[7dt5]], [[7dt6]], [[7dt8]], [[7ejq]], [[7ejr]], [[7erj]], [[7eri]] – hTTR (mutant) + inhibitor<br /> | + | **[[3nes]], [[3nex]], [[7dt3]], [[7dt5]], [[7dt6]], [[7dt8]], [[7ejq]], [[7ejr]], [[7erj]], [[7eri]], [[8ii1]], [[8ii2]], [[8ii3]], [[8ii4]], [[8w43]] – hTTR (mutant) + inhibitor<br /> |
**[[1e3f]], [[1e4h]], [[1e5a]], [[2b15]], [[5hjg]], [[5l4j]] – hTTR + phenol derivative<br /> | **[[1e3f]], [[1e4h]], [[1e5a]], [[2b15]], [[5hjg]], [[5l4j]] – hTTR + phenol derivative<br /> | ||
**[[4l1s]] - hTTR + benzamide derivative<br /> | **[[4l1s]] - hTTR + benzamide derivative<br /> | ||
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**[[1y1d]], [[2b77]], [[2b9a]], [[3d2t]], [[3fc8]], [[3fcb]], [[2f7i]], [[4ikl]], [[4ikk]], [[4ikl]], [[4iki]], [[4ik7]], [[4ik6]], [[4iiz]], [[4ikj]], [[5l4i]], [[6e70]], [[6d0w]] – hTTR + NSAID drug<br /> | **[[1y1d]], [[2b77]], [[2b9a]], [[3d2t]], [[3fc8]], [[3fcb]], [[2f7i]], [[4ikl]], [[4ikk]], [[4ikl]], [[4iki]], [[4ik7]], [[4ik6]], [[4iiz]], [[4ikj]], [[5l4i]], [[6e70]], [[6d0w]] – hTTR + NSAID drug<br /> | ||
| - | **[[4i89]], [[6e78]], [[6e73]], [[7erk]] - hTTR (mutant) + NSAID drug<br /> | + | **[[4i89]], [[6e78]], [[6e73]], [[7erk]], [[7ycq]] - hTTR (mutant) + NSAID drug<br /> |
| + | **[[8aww]], [[8ig1]] - hTTR + non-NSAID drug<br /> | ||
**[[4i87]], [[4i85]] - hTTR (mutant) + fibrillogenesis inhibitor <br /> | **[[4i87]], [[4i85]] - hTTR (mutant) + fibrillogenesis inhibitor <br /> | ||
**[[3b56]] – hTTR + salicylic acid derivative<br /> | **[[3b56]] – hTTR + salicylic acid derivative<br /> | ||
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**[[4pwi]] - hTTR (mutant) + rosamariic acid<br /> | **[[4pwi]] - hTTR (mutant) + rosamariic acid<br /> | ||
**[[4pwj]], [[4pwk]] - hTTR (mutant) + propolis<br /> | **[[4pwj]], [[4pwk]] - hTTR (mutant) + propolis<br /> | ||
| - | **[[4d7b]], [[6suh]], [[6sug]] - hTTR + tolcapone analog<br /> | + | **[[4d7b]], [[6suh]], [[6sug]], [[8c85]], [[8c86]] - hTTR + tolcapone analog<br /> |
| - | **[[5a6i]], [[6xtk]], [[6txw]], [[6txv]] - hTTR (mutant) + tolcapone<br /> | + | **[[5a6i]], [[6xtk]], [[6txw]], [[6txv]], [[7ybr]] - hTTR (mutant) + tolcapone<br /> |
| - | **[[5aks]], [[5akt]], [[5al0]]- hTTR + resveratrol<br /> | + | **[[5aks]], [[5akt]], [[5al0]], [[7q9o]] - hTTR + resveratrol<br /> |
| + | **[[8w42]], [[8w44]] - hTTR (mutant) + resveratol <br /> | ||
**[[5al8]] - hTTR + daidzein glucuronide<br /> | **[[5al8]] - hTTR + daidzein glucuronide<br /> | ||
**[[4y9b]], [[4y9c]], [[4y9e]], [[4y9f]], [[4y9g]] - hTTR (mutant) + mangostin<br /> | **[[4y9b]], [[4y9c]], [[4y9e]], [[4y9f]], [[4y9g]] - hTTR (mutant) + mangostin<br /> | ||
| - | **[[4wnj]] - hTTR + quercetin<br /> | + | **[[4wnj]], [[7z60]] - hTTR + quercetin derivative<br /> |
**[[5l4f]] - hTTR + cresol derivative<br /> | **[[5l4f]] - hTTR + cresol derivative<br /> | ||
**[[4wns]], [[5u48]], [[5u49]], [[5u4a]], [[5u4b]], [[5u4c]], [[5u4d]], [[5u4e]], [[5u4f]] [[5u4g]] - hTTR + stilbene derivative<br /> | **[[4wns]], [[5u48]], [[5u49]], [[5u4a]], [[5u4b]], [[5u4c]], [[5u4d]], [[5u4e]], [[5u4f]] [[5u4g]] - hTTR + stilbene derivative<br /> | ||
| + | **[[8w45]], [[8w46]] - hTTR (mutant) + stilbene derivative<br /> | ||
**[[4wo0]] - hTTR + apigenin<br /> | **[[4wo0]] - hTTR + apigenin<br /> | ||
| + | **[[8w47]] - hTTR (mutant) + isorhapontigenin<br /> | ||
| + | **[[7w9q]], [[7w9r]] - hTTR (mutant) + naringenin derivative<br /> | ||
**[[5boj]] - hTTR + gemfibrozil<br /> | **[[5boj]] - hTTR + gemfibrozil<br /> | ||
**[[7acu]] - hTTR + benzbromarone<br /> | **[[7acu]] - hTTR + benzbromarone<br /> | ||
Current revision
3D structures of transthyretin
Updated on 23-January-2024 - For a general description of the protein see Transthyretin
