7zv9
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of FLT3 in complex with a monomeric FLT3 Ligand variant== | |
| - | + | <StructureSection load='7zv9' size='340' side='right'caption='[[7zv9]], [[Resolution|resolution]] 4.51Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[7zv9]] is a 16 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7ZV9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7ZV9 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7zv9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7zv9 OCA], [https://pdbe.org/7zv9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7zv9 RCSB], [https://www.ebi.ac.uk/pdbsum/7zv9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7zv9 ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/FLT3L_HUMAN FLT3L_HUMAN] Stimulates the proliferation of early hematopoietic cells by activating FLT3. Synergizes well with a number of other colony stimulating factors and interleukins. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Pannecoucke E]] | ||
| + | [[Category: Savvides SN]] | ||
Revision as of 05:36, 31 May 2023
Crystal structure of FLT3 in complex with a monomeric FLT3 Ligand variant
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