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3ps4

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Current revision (10:00, 6 September 2023) (edit) (undo)
 
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<StructureSection load='3ps4' size='340' side='right'caption='[[3ps4]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
<StructureSection load='3ps4' size='340' side='right'caption='[[3ps4]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3ps4]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PS4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PS4 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3ps4]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PS4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PS4 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MAST1, KIAA0973 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ps4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ps4 OCA], [https://pdbe.org/3ps4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ps4 RCSB], [https://www.ebi.ac.uk/pdbsum/3ps4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ps4 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ps4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ps4 OCA], [https://pdbe.org/3ps4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ps4 RCSB], [https://www.ebi.ac.uk/pdbsum/3ps4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ps4 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/MAST1_HUMAN MAST1_HUMAN]] Appears to link the dystrophin/utrophin network with microtubule filaments via the syntrophins. Phosphorylation of DMD or UTRN may modulate their affinities for associated proteins (By similarity).[UniProtKB:Q9R1L5]
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[https://www.uniprot.org/uniprot/MAST1_HUMAN MAST1_HUMAN] Appears to link the dystrophin/utrophin network with microtubule filaments via the syntrophins. Phosphorylation of DMD or UTRN may modulate their affinities for associated proteins (By similarity).[UniProtKB:Q9R1L5]
==See Also==
==See Also==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Non-specific serine/threonine protein kinase]]
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[[Category: Arrowsmith CH]]
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[[Category: Arrowsmith, C H]]
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[[Category: Bountra C]]
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[[Category: Bountra, C]]
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[[Category: Cocking R]]
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[[Category: Cocking, R]]
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[[Category: Doyle DA]]
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[[Category: Delft, F von]]
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[[Category: Edwards A]]
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[[Category: Doyle, D A]]
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[[Category: Elkins JM]]
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[[Category: Edwards, A]]
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[[Category: Knapp S]]
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[[Category: Elkins, J M]]
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[[Category: Krojer T]]
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[[Category: Knapp, S]]
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[[Category: Muniz JRC]]
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[[Category: Krojer, T]]
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[[Category: Pike ACW]]
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[[Category: Muniz, J R.C]]
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[[Category: Roos A]]
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[[Category: Pike, A C.W]]
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[[Category: Salah E]]
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[[Category: Roos, A]]
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[[Category: Savitsky P]]
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[[Category: Structural genomic]]
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[[Category: Sethi R]]
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[[Category: Salah, E]]
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[[Category: Ugochukwu E]]
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[[Category: Savitsky, P]]
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[[Category: Wang J]]
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[[Category: Sethi, R]]
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[[Category: Weigelt J]]
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[[Category: Ugochukwu, E]]
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[[Category: Von Delft F]]
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[[Category: Wang, J]]
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[[Category: Weigelt, J]]
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[[Category: Kinase]]
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[[Category: Pdz domain]]
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[[Category: Serine/threonine-protein kinase]]
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[[Category: Sgc]]
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[[Category: Transferase]]
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Current revision

PDZ domain from Human microtubule-associated serine/threonine-protein kinase 1

PDB ID 3ps4

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