3q0j

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Current revision (13:36, 1 March 2024) (edit) (undo)
 
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<StructureSection load='3q0j' size='340' side='right'caption='[[3q0j]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
<StructureSection load='3q0j' size='340' side='right'caption='[[3q0j]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3q0j]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Myctu Myctu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q0J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3Q0J FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3q0j]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q0J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3Q0J FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CAA:ACETOACETYL-COENZYME+A'>CAA</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3pzk|3pzk]], [[3q0g|3q0g]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CAA:ACETOACETYL-COENZYME+A'>CAA</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">echA8, MT1100, MTV017.23c, Rv1070c ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83332 MYCTU])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Enoyl-CoA_hydratase Enoyl-CoA hydratase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.17 4.2.1.17] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3q0j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q0j OCA], [https://pdbe.org/3q0j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3q0j RCSB], [https://www.ebi.ac.uk/pdbsum/3q0j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3q0j ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3q0j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q0j OCA], [https://pdbe.org/3q0j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3q0j RCSB], [https://www.ebi.ac.uk/pdbsum/3q0j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3q0j ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/ECHA8_MYCTU ECHA8_MYCTU]] Could possibly oxidize fatty acids using specific components (By similarity).
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[https://www.uniprot.org/uniprot/ECHA8_MYCTU ECHA8_MYCTU] Could possibly oxidize fatty acids using specific components (By similarity).
==See Also==
==See Also==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Enoyl-CoA hydratase]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Myctu]]
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[[Category: Mycobacterium tuberculosis H37Rv]]
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[[Category: Bruning, J B]]
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[[Category: Bruning JB]]
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[[Category: Delgado, E]]
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[[Category: Delgado E]]
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[[Category: Ghosh, S]]
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[[Category: Ghosh S]]
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[[Category: Sacchettini, J C]]
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[[Category: Sacchettini JC]]
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[[Category: Structural genomic]]
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[[Category: Crotonase]]
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[[Category: Enoyl coa hydratase]]
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[[Category: Lyase]]
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[[Category: Lyase-lyase inhibitor complex]]
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[[Category: Tbsgc]]
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Current revision

Crystal Structure of the Mycobacterium tuberculosis Crotonase in complex with the Inhibitor AcetoacetylCoA

PDB ID 3q0j

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