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7xl5
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of the H42T/A85G/I86A mutant of a nadp-dependent alcohol dehydrogenase== | |
| - | + | <StructureSection load='7xl5' size='340' side='right'caption='[[7xl5]], [[Resolution|resolution]] 2.60Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[7xl5]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermoanaerobacter_brockii Thermoanaerobacter brockii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7XL5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7XL5 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7xl5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7xl5 OCA], [https://pdbe.org/7xl5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7xl5 RCSB], [https://www.ebi.ac.uk/pdbsum/7xl5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7xl5 ProSAT]</span></td></tr> | |
| - | [[Category: | + | </table> |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/ADH_THEBR ADH_THEBR] Alcohol dehydrogenase with a preference for medium chain secondary alcohols, such as 2-butanol and isopropanol. Has very low activity with primary alcohols, such as ethanol. Under physiological conditions, the enzyme reduces aldehydes and 2-ketones to produce secondary alcohols. Is also active with acetaldehyde and propionaldehyde. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Thermoanaerobacter brockii]] | ||
| + | [[Category: Han X]] | ||
| + | [[Category: Jiang YY]] | ||
| + | [[Category: Li X]] | ||
| + | [[Category: Liu WD]] | ||
| + | [[Category: Qu G]] | ||
| + | [[Category: Sun ZT]] | ||
Revision as of 05:33, 31 May 2023
Crystal structure of the H42T/A85G/I86A mutant of a nadp-dependent alcohol dehydrogenase
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Categories: Large Structures | Thermoanaerobacter brockii | Han X | Jiang YY | Li X | Liu WD | Qu G | Sun ZT
