1h8m

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[[Image:1h8m.gif|left|200px]]
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{{STRUCTURE_1h8m| PDB=1h8m | SCENE= }}
{{STRUCTURE_1h8m| PDB=1h8m | SCENE= }}
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'''SOLUTION STRUCTURE OF YKT6'''
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===SOLUTION STRUCTURE OF YKT6===
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==Overview==
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Ykt6p is a nonsyntaxin SNARE implicated in multiple intracellular membrane trafficking steps. Here we present the structure of the NH2-terminal domain of Ykt6p (Ykt6pN, residues 1 to 140). The structure of Ykt6pN differed entirely from that of syntaxin and resembled the overall fold of the actin regulatory protein, profilin. Like some syntaxins, Ykt6p adopted a folded back conformation in which Ykt6pN bound to its COOH-terminal core domain. The NH2-terminal domain plays an important biological role in the function of Ykt6p, which in vitro studies revealed to include influencing the kinetics and proper assembly of SNARE complexes.
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(as it appears on PubMed at http://www.pubmed.gov), where 11474112 is the PubMed ID number.
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{{ABSTRACT_PUBMED_11474112}}
==About this Structure==
==About this Structure==
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1H8M is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H8M OCA].
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1H8M is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H8M OCA].
==Reference==
==Reference==
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[[Category: Prenylation]]
[[Category: Prenylation]]
[[Category: Transmembrane lipoprotein]]
[[Category: Transmembrane lipoprotein]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 18:34:24 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 06:48:32 2008''

Revision as of 03:48, 1 July 2008

Image:1h8m.png

Template:STRUCTURE 1h8m

SOLUTION STRUCTURE OF YKT6

Template:ABSTRACT PUBMED 11474112

About this Structure

1H8M is a Single protein structure of sequence from Saccharomyces cerevisiae. Full experimental information is available from OCA.

Reference

An autoinhibitory mechanism for nonsyntaxin SNARE proteins revealed by the structure of Ykt6p., Tochio H, Tsui MM, Banfield DK, Zhang M, Science. 2001 Jul 27;293(5530):698-702. PMID:11474112

Page seeded by OCA on Tue Jul 1 06:48:32 2008

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