7zxa
From Proteopedia
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- | '''Unreleased structure''' | ||
- | + | ==Crystal structure of human cathepsin L with covalently bound aloxistatin (E-64D)== | |
- | + | <StructureSection load='7zxa' size='340' side='right'caption='[[7zxa]], [[Resolution|resolution]] 1.60Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[7zxa]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7ZXA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7ZXA FirstGlance]. <br> | |
- | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=E6D:ETHYL+(3S)-3-HYDROXY-4-({(2S)-4-METHYL-1-[(3-METHYLBUTYL)AMINO]-1-OXOPENTAN-2-YL}AMINO)-4-OXOBUTANOATE'>E6D</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=P6G:HEXAETHYLENE+GLYCOL'>P6G</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr> | |
- | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7zxa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7zxa OCA], [https://pdbe.org/7zxa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7zxa RCSB], [https://www.ebi.ac.uk/pdbsum/7zxa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7zxa ProSAT]</span></td></tr> |
+ | </table> | ||
+ | == Function == | ||
+ | [https://www.uniprot.org/uniprot/CATL1_HUMAN CATL1_HUMAN] Important for the overall degradation of proteins in lysosomes. | ||
+ | __TOC__ | ||
+ | </StructureSection> | ||
+ | [[Category: Homo sapiens]] | ||
+ | [[Category: Large Structures]] | ||
+ | [[Category: Chapman HN]] | ||
+ | [[Category: Ewert W]] | ||
+ | [[Category: Falke S]] | ||
+ | [[Category: Guenther S]] | ||
+ | [[Category: Hinrichs W]] | ||
+ | [[Category: Karnicar K]] | ||
+ | [[Category: Lieske J]] | ||
+ | [[Category: Lindic N]] | ||
+ | [[Category: Loboda J]] | ||
+ | [[Category: Meents A]] | ||
+ | [[Category: Reinke PYA]] | ||
+ | [[Category: Sekirnik A]] | ||
+ | [[Category: Turk D]] | ||
+ | [[Category: Usenik A]] |
Revision as of 05:36, 31 May 2023
Crystal structure of human cathepsin L with covalently bound aloxistatin (E-64D)
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Categories: Homo sapiens | Large Structures | Chapman HN | Ewert W | Falke S | Guenther S | Hinrichs W | Karnicar K | Lieske J | Lindic N | Loboda J | Meents A | Reinke PYA | Sekirnik A | Turk D | Usenik A