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3qgz

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Re-investigated high resolution crystal structure of histidine triad nucleotide-binding protein 1 (HINT1) from rabbit complexed with adenosine

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 <StructureSection load='3qgz' size='340' side='right'caption='[[3qgz]], [[Resolution|resolution]] 1.10&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[3qgz]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/European_rabbit European rabbit]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3llj 3llj]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QGZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QGZ FirstGlance]. <br>
+<table><tr><td colspan='2'>[[3qgz]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3llj 3llj]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QGZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QGZ FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADN:ADENOSINE'>ADN</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.1&#8491;</td></tr>
-<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3llj|3llj]], [[1rzy|1rzy]], [[3rhn|3rhn]], [[4rhn|4rhn]], [[5rhn|5rhn]], [[6rhn|6rhn]]</div></td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADN:ADENOSINE'>ADN</scene></td></tr>
-<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HINT1, HINT ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9986 European rabbit])</td></tr>
 <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qgz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qgz OCA], [https://pdbe.org/3qgz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qgz RCSB], [https://www.ebi.ac.uk/pdbsum/3qgz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qgz ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[https://www.uniprot.org/uniprot/HINT1_RABIT HINT1_RABIT]] Hydrolyzes adenosine 5'-monophosphoramidate substrates such as AMP-morpholidate, AMP-N-alanine methyl ester, AMP-alpha-acetyl lysine methyl ester and AMP-NH2.
+[https://www.uniprot.org/uniprot/HINT1_RABIT HINT1_RABIT] Hydrolyzes adenosine 5'-monophosphoramidate substrates such as AMP-morpholidate, AMP-N-alanine methyl ester, AMP-alpha-acetyl lysine methyl ester and AMP-NH2.
-<div style="background-color:#fffaf0;">
-== Publication Abstract from PubMed ==
-Histidine triad nucleotide-binding protein 1 (HINT1) represents the most ancient and widespread branch in the histidine-triad protein superfamily. HINT1 plays an important role in various biological processes and has been found in many species. Here, the first complete structure of the rabbit HINT1-adenosine complex is reported at 1.10 A resolution, which is one of the highest resolutions obtained for a HINT1 structure. The final structure has an R(cryst) of 14.25% (R(free) = 16.77%) and the model exhibits good stereochemical qualities. A detailed analysis of the atomic resolution data allowed an update of the details of the protein structure in comparison to previously published data.
-High-resolution X-ray structure of the rabbit histidine triad nucleotide-binding protein 1 (rHINT1)-adenosine complex at 1.10 A resolution.,Dolot R, Ozga M, Krakowiak A, Nawrot B Acta Crystallogr D Biol Crystallogr. 2011 Jul;67(Pt 7):601-7. doi:, 10.1107/S0907444911015605. Epub 2011 Jun 14. PMID:21697598<ref>PMID:21697598</ref>
-From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
-</div>
-<div class="pdbe-citations 3qgz" style="background-color:#fffaf0;"></div>
 ==See Also==
 *[[Histidine triad nucleotide-binding protein 3D structures|Histidine triad nucleotide-binding protein 3D structures]]
-== References ==
-<references/>
 __TOC__
 </StructureSection>
-[[Category: European rabbit]]
 [[Category: Large Structures]]
-[[Category: Dolot, R M]]
+[[Category: Oryctolagus cuniculus]]
-[[Category: Krakowiak, A]]
+[[Category: Dolot RM]]
-[[Category: Nawrot, B]]
+[[Category: Krakowiak A]]
-[[Category: Ozga, M]]
+[[Category: Nawrot B]]
-[[Category: Stec, W J]]
+[[Category: Ozga M]]
-[[Category: Adenosine 5'-monophosphoramidase]]
+[[Category: Stec WJ]]
-[[Category: Hint protein]]
-[[Category: Hit family protein]]
-[[Category: Hydrolase]]

3qgz

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Current revision

Re-investigated high resolution crystal structure of histidine triad nucleotide-binding protein 1 (HINT1) from rabbit complexed with adenosine

Structural highlights

Function

See Also

Contents

Proteopedia Page Contributors and Editors (what is this?)

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