1hbi

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[[Image:1hbi.gif|left|200px]]
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{{Seed}}
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{{STRUCTURE_1hbi| PDB=1hbi | SCENE= }}
{{STRUCTURE_1hbi| PDB=1hbi | SCENE= }}
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'''CRYSTAL STRUCTURE OF OXYGENATED SCAPHARCA DIMERIC HEMOGLOBIN AT 1.7 ANGSTROMS RESOLUTION'''
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===CRYSTAL STRUCTURE OF OXYGENATED SCAPHARCA DIMERIC HEMOGLOBIN AT 1.7 ANGSTROMS RESOLUTION===
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==Overview==
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The crystal structure of the cooperative dimeric hemoglobin from the blood clam Scapharca inaequivalvis has been determined in the oxygenated state and refined to an R-factor of 0.157 at 1.7-A resolution. The structure is very similar to the carbon monoxide-liganded form with subtle differences in ligand binding geometry. Oxygen binds to the heme iron in a bent conformation with Fe-O-O angles of 135 degrees and 150 degrees for the two subunits. These observed angles are lower than the equivalent angles in the carbon monoxide-liganded form and intermediate between the angles observed in structures of oxygenated sperm whale myoglobin and oxygenated human hemoglobin. This third high resolution structure of Scapharca dimeric hemoglobin permits a detailed analysis of the water structure in the highly hydrated interface between subunits.
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(as it appears on PubMed at http://www.pubmed.gov), where 7929217 is the PubMed ID number.
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{{ABSTRACT_PUBMED_7929217}}
==About this Structure==
==About this Structure==
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[[Category: Junior, W E.Royer.]]
[[Category: Junior, W E.Royer.]]
[[Category: Oxygen transport]]
[[Category: Oxygen transport]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 18:40:03 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 07:56:31 2008''

Revision as of 04:56, 1 July 2008

Template:STRUCTURE 1hbi

CRYSTAL STRUCTURE OF OXYGENATED SCAPHARCA DIMERIC HEMOGLOBIN AT 1.7 ANGSTROMS RESOLUTION

Template:ABSTRACT PUBMED 7929217

About this Structure

1HBI is a Single protein structure of sequence from Scapharca inaequivalvis. Full crystallographic information is available from OCA.

Reference

Crystal structure of oxygenated Scapharca dimeric hemoglobin at 1.7-A resolution., Condon PJ, Royer WE Jr, J Biol Chem. 1994 Oct 14;269(41):25259-67. PMID:7929217

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