7t1e
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of monomeric and dimeric human CCL20== | |
| - | + | <StructureSection load='7t1e' size='340' side='right'caption='[[7t1e]], [[Resolution|resolution]] 1.46Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[7t1e]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7T1E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7T1E FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=SIN:SUCCINIC+ACID'>SIN</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7t1e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7t1e OCA], [https://pdbe.org/7t1e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7t1e RCSB], [https://www.ebi.ac.uk/pdbsum/7t1e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7t1e ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: Peterson | + | == Function == |
| - | [[Category: Volkman | + | [https://www.uniprot.org/uniprot/CCL20_HUMAN CCL20_HUMAN] Chemotactic factor that attracts lymphocytes and, slightly, neutrophils, but not monocytes. Inhibits proliferation of myeloid progenitors in colony formation assays. May be involved in formation and function of the mucosal lymphoid tissues by attracting lymphocytes and dendritic cells towards epithelial cells. C-terminal processed forms have been shown to be equally chemotactically active for leukocytes. Possesses antibacterial activity E.coli ATCC 25922 and S.aureus ATCC 29213.<ref>PMID:12149255</ref> |
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Peterson FC]] | ||
| + | [[Category: Riutta SJ]] | ||
| + | [[Category: Volkman BF]] | ||
Revision as of 10:00, 14 December 2022
Structure of monomeric and dimeric human CCL20
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