7tcy
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | The | + | ==The ubiquitin-associated domain of human thirty-eight negative kinase I== |
| - | + | <StructureSection load='7tcy' size='340' side='right'caption='[[7tcy]], [[Resolution|resolution]] 1.54Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[7tcy]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7TCY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7TCY FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7tcy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7tcy OCA], [https://pdbe.org/7tcy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7tcy RCSB], [https://www.ebi.ac.uk/pdbsum/7tcy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7tcy ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: Doukov | + | == Function == |
| - | [[Category: Moody | + | [https://www.uniprot.org/uniprot/TNK1_HUMAN TNK1_HUMAN] Involved in negative regulation of cell growth. Has tumor suppressor properties. Plays a negative regulatory role in the Ras-MAPK pathway. May function in signaling pathways utilized broadly during fetal development and more selectively in adult tissues and in cells of the lymphohematopoietic system. Could specifically be involved in phospholipid signal transduction.<ref>PMID:10873601</ref> <ref>PMID:18974114</ref> |
| - | [[Category: | + | == References == |
| - | [[Category: | + | <references/> |
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Bunn RD]] | ||
| + | [[Category: Doukov T]] | ||
| + | [[Category: Moody DJ]] | ||
| + | [[Category: Nawarathnage S]] | ||
| + | [[Category: Stewart C]] | ||
Revision as of 07:33, 11 January 2023
The ubiquitin-associated domain of human thirty-eight negative kinase I
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