1het

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:1het.gif|left|200px]]
+
{{Seed}}
 +
[[Image:1het.png|left|200px]]
<!--
<!--
Line 9: Line 10:
{{STRUCTURE_1het| PDB=1het | SCENE= }}
{{STRUCTURE_1het| PDB=1het | SCENE= }}
-
'''ATOMIC X-RAY STRUCTURE OF LIVER ALCOHOL DEHYDROGENASE CONTAINING A HYDROXIDE ADDUCT TO NADH'''
+
===ATOMIC X-RAY STRUCTURE OF LIVER ALCOHOL DEHYDROGENASE CONTAINING A HYDROXIDE ADDUCT TO NADH===
-
==Overview==
+
<!--
-
Atomic (1 A) resolution x-ray structures of horse liver alcohol dehydrogenase in complex with NADH revealed the formation of an adduct in the active site between a metal-bound water and NADH. Furthermore, a pronounced distortion of the pyridine ring of NADH was observed. A series of quantum chemical calculations on the water-nicotinamide adduct showed that the puckering of the pyridine ring in the crystal structures can only be reproduced when the water is considered a hydroxide ion. These observations provide fundamental insight into the enzymatic activation of NADH for hydride transfer.
+
The line below this paragraph, {{ABSTRACT_PUBMED_11134046}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 11134046 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_11134046}}
==About this Structure==
==About this Structure==
Line 29: Line 33:
[[Category: Merli, A.]]
[[Category: Merli, A.]]
[[Category: Morris, R J.]]
[[Category: Morris, R J.]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 18:46:39 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 08:05:30 2008''

Revision as of 05:05, 1 July 2008

Image:1het.png

Template:STRUCTURE 1het

ATOMIC X-RAY STRUCTURE OF LIVER ALCOHOL DEHYDROGENASE CONTAINING A HYDROXIDE ADDUCT TO NADH

Template:ABSTRACT PUBMED 11134046

About this Structure

1HET is a Single protein structure of sequence from Equus caballus. Full crystallographic information is available from OCA.

Reference

On the enzymatic activation of NADH., Meijers R, Morris RJ, Adolph HW, Merli A, Lamzin VS, Cedergren-Zeppezauer ES, J Biol Chem. 2001 Mar 23;276(12):9316-21. Epub 2000 Dec 28. PMID:11134046

Page seeded by OCA on Tue Jul 1 08:05:30 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1het"
Personal tools