1hig

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{{STRUCTURE_1hig| PDB=1hig | SCENE= }}
{{STRUCTURE_1hig| PDB=1hig | SCENE= }}
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'''THREE-DIMENSIONAL STRUCTURE OF RECOMBINANT HUMAN INTERFERON-GAMMA.'''
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===THREE-DIMENSIONAL STRUCTURE OF RECOMBINANT HUMAN INTERFERON-GAMMA.===
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==Overview==
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The x-ray crystal structure of recombinant human interferon-gamma has been determined with the use of multiple-isomorphous-replacement techniques. Interferon-gamma, which is dimeric in solution, crystallizes with two dimers related by a noncrystallographic twofold axis in the asymmetric unit. The protein is primarily alpha helical, with six helices in each subunit that comprise approximately 62 percent of the structure; there is no beta sheet. The dimeric structure of human interferon-gamma is stabilized by the intertwining of helices across the subunit interface with multiple intersubunit interactions.
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The line below this paragraph, {{ABSTRACT_PUBMED_1902591}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 1902591 is the PubMed ID number.
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{{ABSTRACT_PUBMED_1902591}}
==About this Structure==
==About this Structure==
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[[Category: Vijay-Kumar, S.]]
[[Category: Vijay-Kumar, S.]]
[[Category: Glycoprotein]]
[[Category: Glycoprotein]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 18:52:40 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 08:13:41 2008''

Revision as of 05:13, 1 July 2008

Image:1hig.png

Template:STRUCTURE 1hig

THREE-DIMENSIONAL STRUCTURE OF RECOMBINANT HUMAN INTERFERON-GAMMA.

Template:ABSTRACT PUBMED 1902591

About this Structure

1HIG is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Three-dimensional structure of recombinant human interferon-gamma., Ealick SE, Cook WJ, Vijay-Kumar S, Carson M, Nagabhushan TL, Trotta PP, Bugg CE, Science. 1991 May 3;252(5006):698-702. PMID:1902591

Page seeded by OCA on Tue Jul 1 08:13:41 2008

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