3rru

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Current revision (09:39, 30 October 2024) (edit) (undo)
 
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<StructureSection load='3rru' size='340' side='right'caption='[[3rru]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
<StructureSection load='3rru' size='340' side='right'caption='[[3rru]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3rru]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RRU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3RRU FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3rru]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RRU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3RRU FirstGlance]. <br>
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</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">hCG_32771, tom1-like, TOM1L1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3rru FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rru OCA], [https://pdbe.org/3rru PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3rru RCSB], [https://www.ebi.ac.uk/pdbsum/3rru PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3rru ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3rru FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rru OCA], [https://pdbe.org/3rru PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3rru RCSB], [https://www.ebi.ac.uk/pdbsum/3rru PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3rru ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/TM1L1_HUMAN TM1L1_HUMAN] Probable adapter protein involved in signaling pathways. Interacts with the SH2 and SH3 domains of various signaling proteins when it is phosphorylated. May promote FYN activation, possibly by disrupting intramolecular SH3-dependent interactions (By similarity).
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__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Acton, T B]]
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[[Category: Acton TB]]
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[[Category: Ciccosanti, C]]
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[[Category: Ciccosanti C]]
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[[Category: Everett, J K]]
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[[Category: Everett JK]]
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[[Category: Forouhar, F]]
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[[Category: Forouhar F]]
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[[Category: Hunt, J F]]
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[[Category: Hunt JF]]
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[[Category: Lew, S]]
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[[Category: Lew S]]
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[[Category: Montelione, G T]]
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[[Category: Montelione GT]]
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[[Category: Structural genomic]]
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[[Category: Patel D]]
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[[Category: Patel, D]]
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[[Category: Seetharaman J]]
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[[Category: Seetharaman, J]]
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[[Category: Tong L]]
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[[Category: Tong, L]]
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[[Category: Wang H]]
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[[Category: Wang, H]]
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[[Category: Xiao R]]
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[[Category: Xiao, R]]
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[[Category: Nesg]]
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[[Category: Psi-biology]]
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[[Category: Signaling protein]]
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[[Category: Src-activating and signaling molecule protein]]
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[[Category: Super-helical protein]]
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[[Category: Target of myb-like protein 1]]
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Current revision

X-ray crystal structure of the VHS domain of human TOM1-like protein, Northeast Structural Genomics Consortium Target HR3050E

PDB ID 3rru

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