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3rto

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Current revision (12:36, 14 March 2024) (edit) (undo)
 
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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3rto]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RTO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3RTO FirstGlance]. <br>
<table><tr><td colspan='2'>[[3rto]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RTO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3RTO FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3rto FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rto OCA], [https://pdbe.org/3rto PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3rto RCSB], [https://www.ebi.ac.uk/pdbsum/3rto PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3rto ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3rto FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rto OCA], [https://pdbe.org/3rto PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3rto RCSB], [https://www.ebi.ac.uk/pdbsum/3rto PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3rto ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/INS_PIG INS_PIG]] Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
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[https://www.uniprot.org/uniprot/INS_PIG INS_PIG] Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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We demonstrate a general strategy for determining structures from showers of microcrystals. It uses acoustic droplet ejection to transfer 2.5 nL droplets from the surface of microcrystal slurries, through the air, onto mounting micromesh pins. Individual microcrystals are located by raster-scanning a several-micrometer X-ray beam across the cryocooled micromeshes. X-ray diffraction data sets merged from several micrometer-sized crystals are used to determine 1.8 A resolution crystal structures.
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Acoustically Mounted Microcrystals Yield High-Resolution X-ray Structures.,Soares AS, Engel MA, Stearns R, Datwani S, Olechno J, Ellson R, Skinner JM, Allaire M, Orville AM Biochemistry. 2011 May 9. PMID:21542590<ref>PMID:21542590</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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<div class="pdbe-citations 3rto" style="background-color:#fffaf0;"></div>
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==See Also==
==See Also==
*[[Insulin 3D Structures|Insulin 3D Structures]]
*[[Insulin 3D Structures|Insulin 3D Structures]]
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== References ==
 
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<references/>
 
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Sus scrofa]]
[[Category: Sus scrofa]]
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[[Category: Allaire, M]]
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[[Category: Allaire M]]
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[[Category: Datwani, S]]
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[[Category: Datwani S]]
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[[Category: Ellson, R]]
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[[Category: Ellson R]]
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[[Category: Engel, M A]]
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[[Category: Engel MA]]
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[[Category: Olechno, J]]
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[[Category: Olechno J]]
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[[Category: Orville, A M]]
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[[Category: Orville AM]]
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[[Category: Skinner, J M]]
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[[Category: Skinner JM]]
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[[Category: Soares, A S]]
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[[Category: Soares AS]]
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[[Category: Stearns, R]]
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[[Category: Stearns R]]
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[[Category: Hormone]]
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Current revision

Acoustically mounted porcine insulin microcrystals yield an X-ray SAD structure

PDB ID 3rto

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