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Beta-lactamase
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(Difference between revisions)
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*Class D are cloxacilanases<br /> | *Class D are cloxacilanases<br /> | ||
*Carbapenemase (Car) are Blac with wide hydrolytic capacities. Car can hydrolyze penicillins, cephalosporins, monobactams and carbapenems. <br /> | *Carbapenemase (Car) are Blac with wide hydrolytic capacities. Car can hydrolyze penicillins, cephalosporins, monobactams and carbapenems. <br /> | ||
| - | *Extended-spectrum Blac class A (ESBL) hydrolyze penicillins but not cephalosporins. | + | *Extended-spectrum Blac class A (ESBL) hydrolyze penicillins but not cephalosporins.<br /> |
| + | *Serine beta-lactamase (ClbP) has a serine-active site. | ||
== Relevance == | == Relevance == | ||
Revision as of 10:20, 2 November 2022
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References
- ↑ King D, Strynadka N. Crystal structure of New Delhi metallo-beta-lactamase reveals molecular basis for antibiotic resistance. Protein Sci. 2011 Sep;20(9):1484-91. doi: 10.1002/pro.697. Epub 2011 Aug, 2. PMID:21774017 doi:10.1002/pro.697
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