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8dcj
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==[A:T] Self-Assembled 3D DNA Rhombohedral Tensegrity Triangle== | |
| + | <StructureSection load='8dcj' size='340' side='right'caption='[[8dcj]], [[Resolution|resolution]] 3.33Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[8dcj]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8DCJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8DCJ FirstGlance]. <br> | ||
| + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8dcj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8dcj OCA], [https://pdbe.org/8dcj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8dcj RCSB], [https://www.ebi.ac.uk/pdbsum/8dcj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8dcj ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | <p class="Text" style="margin: 0in 0in 8pt; text-align: justify; line-height: 24px; font-size: 12pt; font-family: "Times New Roman", serif; color: rgb(0, 0, 0);">Non-canonical interactions in DNA remain under-explored in DNA nanotechnology. Recently, many structures with non-canonical motifs have been discovered, notably a hexagonal arrangement of typically rhombohedral DNA tensegrity triangles that forms through non-canonical sticky end interactions. Here, we find a series of mechanisms to program a hexagonal arrangement using: the sticky end sequence; triangle edge torsional stress; and crystallization condition. We showcase cross-talking between Watson-Crick and non-canonical sticky ends in which the ratio between the two dictates segregation by crystal forms or combination into composite crystals. Finally, we develop a method for reconfiguring the long-range geometry of formed crystals from rhombohedral to hexagonal and <italic>vice versa</italic>. These data demonstrate fine control over non-canonical motifs and their topological self-assembly. This will vastly increase the programmability, functionality, and versatility of rationally designed DNA constructs.<o:p></o:p></p>. | ||
| - | + | Programmable 3D Hexagonal Geometry of DNA Tensegrity Triangles.,Lu B, Woloszyn K, Ohayon YP, Yang B, Zhang C, Mao C, Seeman NC, Vecchioni S, Sha R Angew Chem Int Ed Engl. 2022 Dec 15. doi: 10.1002/anie.202213451. PMID:36520622<ref>PMID:36520622</ref> | |
| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| - | [[Category: | + | </div> |
| + | <div class="pdbe-citations 8dcj" style="background-color:#fffaf0;"></div> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Synthetic construct]] | ||
| + | [[Category: Lu B]] | ||
| + | [[Category: Mao C]] | ||
| + | [[Category: Ohayon YP]] | ||
| + | [[Category: Seeman NC]] | ||
| + | [[Category: Sha R]] | ||
| + | [[Category: Vecchioni S]] | ||
Revision as of 07:31, 18 January 2023
[A:T] Self-Assembled 3D DNA Rhombohedral Tensegrity Triangle
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Categories: Large Structures | Synthetic construct | Lu B | Mao C | Ohayon YP | Seeman NC | Sha R | Vecchioni S
