7tep
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
==Crystal structure of a Cu-bound cytochrome cb562 variant in the presence of reductant== | ==Crystal structure of a Cu-bound cytochrome cb562 variant in the presence of reductant== | ||
| - | <StructureSection load='7tep' size='340' side='right'caption='[[7tep]]' scene=''> | + | <StructureSection load='7tep' size='340' side='right'caption='[[7tep]], [[Resolution|resolution]] 2.70Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7TEP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7TEP FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[7tep]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7TEP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7TEP FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7tep FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7tep OCA], [https://pdbe.org/7tep PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7tep RCSB], [https://www.ebi.ac.uk/pdbsum/7tep PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7tep ProSAT]</span></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=HEC:HEME+C'>HEC</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7tep FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7tep OCA], [https://pdbe.org/7tep PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7tep RCSB], [https://www.ebi.ac.uk/pdbsum/7tep PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7tep ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/C562_ECOLX C562_ECOLX] Electron-transport protein of unknown function. | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | Herein we describe a designed protein building block whose self-assembly behaviour is dually gated by the redox state of disulphide bonds and the identity of exogenous metal ions. This protein construct is shown - through extensive structural and biophysical characterization - to access five distinct oligomeric states, exemplifying how the complex interplay between hydrophobic, metal-ligand, and reversible covalent interactions could be harnessed to obtain multiple, responsive protein architectures from a single building block. | ||
| + | |||
| + | Redox- and metal-directed structural diversification in designed metalloprotein assemblies.,Kakkis A, Golub E, Choi TS, Tezcan FA Chem Commun (Camb). 2022 Jun 16;58(49):6958-6961. doi: 10.1039/d2cc02440c. PMID:35642584<ref>PMID:35642584</ref> | ||
| + | |||
| + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
| + | </div> | ||
| + | <div class="pdbe-citations 7tep" style="background-color:#fffaf0;"></div> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Cytochrome C 3D structures|Cytochrome C 3D structures]] | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Escherichia coli]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: | + | [[Category: Golub E]] |
| + | [[Category: Kakkis A]] | ||
Revision as of 07:46, 11 January 2023
Crystal structure of a Cu-bound cytochrome cb562 variant in the presence of reductant
| |||||||||||
