7xxk
From Proteopedia
(Difference between revisions)
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==Crystal structure of SARS-CoV-2 N-CTD in complex with GMP== | ==Crystal structure of SARS-CoV-2 N-CTD in complex with GMP== | ||
| - | <StructureSection load='7xxk' size='340' side='right'caption='[[7xxk]]' scene=''> | + | <StructureSection load='7xxk' size='340' side='right'caption='[[7xxk]], [[Resolution|resolution]] 2.00Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7XXK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7XXK FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[7xxk]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Severe_acute_respiratory_syndrome_coronavirus_2 Severe acute respiratory syndrome coronavirus 2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7XXK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7XXK FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7xxk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7xxk OCA], [https://pdbe.org/7xxk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7xxk RCSB], [https://www.ebi.ac.uk/pdbsum/7xxk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7xxk ProSAT]</span></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5GP:GUANOSINE-5-MONOPHOSPHATE'>5GP</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GMP:GUANOSINE'>GMP</scene>, <scene name='pdbligand=GUN:GUANINE'>GUN</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SCN:THIOCYANATE+ION'>SCN</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7xxk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7xxk OCA], [https://pdbe.org/7xxk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7xxk RCSB], [https://www.ebi.ac.uk/pdbsum/7xxk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7xxk ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/NCAP_SARS2 NCAP_SARS2] Packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication. | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Nucleoprotein 3D structures|Nucleoprotein 3D structures]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: | + | [[Category: Severe acute respiratory syndrome coronavirus 2]] |
| + | [[Category: Lei J]] | ||
| + | [[Category: Ni XC]] | ||
| + | [[Category: Zhou RJ]] | ||
Current revision
Crystal structure of SARS-CoV-2 N-CTD in complex with GMP
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