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3s9u
From Proteopedia
(Difference between revisions)
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<StructureSection load='3s9u' size='340' side='right'caption='[[3s9u]], [[Resolution|resolution]] 1.90Å' scene=''> | <StructureSection load='3s9u' size='340' side='right'caption='[[3s9u]], [[Resolution|resolution]] 1.90Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3s9u]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[3s9u]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_anthracis Bacillus anthracis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3S9U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3S9U FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5DR:6-ETHYL-5-[3-(4-METHOXYBIPHENYL-3-YL)PROP-1-YN-1-YL]PYRIMIDINE-2,4-DIAMINE'>5DR</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5DR:6-ETHYL-5-[3-(4-METHOXYBIPHENYL-3-YL)PROP-1-YN-1-YL]PYRIMIDINE-2,4-DIAMINE'>5DR</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr> | |
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3s9u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3s9u OCA], [https://pdbe.org/3s9u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3s9u RCSB], [https://www.ebi.ac.uk/pdbsum/3s9u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3s9u ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3s9u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3s9u OCA], [https://pdbe.org/3s9u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3s9u RCSB], [https://www.ebi.ac.uk/pdbsum/3s9u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3s9u ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | + | [https://www.uniprot.org/uniprot/Q81R22_BACAN Q81R22_BACAN] Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity).[PIRNR:PIRNR000194] | |
==See Also== | ==See Also== | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Bacillus anthracis]] |
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Anderson | + | [[Category: Anderson AC]] |
| - | [[Category: Beierlein | + | [[Category: Beierlein JM]] |
| - | + | ||
Current revision
Bacillus anthracis Dihydrofolate Reductase bound to propargyl-linked TMP analog, UCP120J
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