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3sab

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Current revision (12:51, 14 March 2024) (edit) (undo)
 
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<StructureSection load='3sab' size='340' side='right'caption='[[3sab]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
<StructureSection load='3sab' size='340' side='right'caption='[[3sab]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3sab]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/9hiv1 9hiv1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SAB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SAB FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3sab]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SAB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SAB FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=F78:3-HYDROXY-N-[(2S,3R)-3-HYDROXY-4-{[(4-METHOXYPHENYL)SULFONYL](3-PHENYLPROPYL)AMINO}-1-PHENYLBUTAN-2-YL]BENZAMIDE'>F78</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3sa3|3sa3]], [[3sa4|3sa4]], [[3sa5|3sa5]], [[3sa6|3sa6]], [[3sa7|3sa7]], [[3sa8|3sa8]], [[3sa9|3sa9]], [[3saa|3saa]], [[3sac|3sac]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=F78:3-HYDROXY-N-[(2S,3R)-3-HYDROXY-4-{[(4-METHOXYPHENYL)SULFONYL](3-PHENYLPROPYL)AMINO}-1-PHENYLBUTAN-2-YL]BENZAMIDE'>F78</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">gag-pol, pol ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11676 9HIV1])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3sab FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3sab OCA], [https://pdbe.org/3sab PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3sab RCSB], [https://www.ebi.ac.uk/pdbsum/3sab PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3sab ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3sab FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3sab OCA], [https://pdbe.org/3sab PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3sab RCSB], [https://www.ebi.ac.uk/pdbsum/3sab PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3sab ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/O38732_9HIV1 O38732_9HIV1]
==See Also==
==See Also==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human immunodeficiency virus 1]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Nalam, M N.L]]
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[[Category: Nalam MNL]]
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[[Category: Schiffer, C A]]
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[[Category: Schiffer CA]]
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[[Category: Aid]]
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[[Category: Aspartyl protease]]
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[[Category: Drug design]]
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[[Category: Drug resistance]]
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[[Category: Hiv-1 protease]]
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[[Category: Hydrolase-hydrolase inhibitor complex]]
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[[Category: Protease inhibitor]]
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Current revision

Crystal structure of wild-type HIV-1 protease in complex with AF78

PDB ID 3sab

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