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3ssj

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Current revision (13:06, 14 March 2024) (edit) (undo)
 
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<StructureSection load='3ssj' size='340' side='right'caption='[[3ssj]], [[Resolution|resolution]] 1.40&Aring;' scene=''>
<StructureSection load='3ssj' size='340' side='right'caption='[[3ssj]], [[Resolution|resolution]] 1.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3ssj]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Metth Metth]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SSJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SSJ FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3ssj]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanothermobacter_thermautotrophicus_str._Delta_H Methanothermobacter thermautotrophicus str. Delta H]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SSJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SSJ FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FNU:6-AMINO-5-FLUOROURIDINE+5-(DIHYDROGEN+PHOSPHATE)'>FNU</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.4&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3sec|3sec]], [[3sgu|3sgu]], [[3sw6|3sw6]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FNU:6-AMINO-5-FLUOROURIDINE+5-(DIHYDROGEN+PHOSPHATE)'>FNU</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">1470090, MTH_129, pyrF ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=187420 METTH])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Orotidine-5'-phosphate_decarboxylase Orotidine-5'-phosphate decarboxylase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.23 4.1.1.23] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ssj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ssj OCA], [https://pdbe.org/3ssj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ssj RCSB], [https://www.ebi.ac.uk/pdbsum/3ssj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ssj ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ssj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ssj OCA], [https://pdbe.org/3ssj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ssj RCSB], [https://www.ebi.ac.uk/pdbsum/3ssj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ssj ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/PYRF_METTH PYRF_METTH]] Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).[HAMAP-Rule:MF_01200_A]
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[https://www.uniprot.org/uniprot/PYRF_METTH PYRF_METTH] Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).[HAMAP-Rule:MF_01200_A]
==See Also==
==See Also==
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Metth]]
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[[Category: Methanothermobacter thermautotrophicus str. Delta H]]
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[[Category: Orotidine-5'-phosphate decarboxylase]]
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[[Category: Kotra LP]]
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[[Category: Kotra, L P]]
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[[Category: Liu Y]]
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[[Category: Liu, Y]]
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[[Category: Pai EF]]
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[[Category: Pai, E F]]
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[[Category: 5-fluoro-6-amino-ump]]
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[[Category: Decarboxylase]]
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[[Category: Lyase]]
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[[Category: Methanothermobacter thermautotrophicus]]
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[[Category: Orotidine 5'-monophosphate decarboxylase]]
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Current revision

Crystal structure of Methanothermobacter thermautotrophicus orotidine 5'-monophosphate decarboxylase complexed with 5-fluoro-6-amino-UMP

PDB ID 3ssj

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