Journal:Acta Cryst F:S2053230X22006586
From Proteopedia
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<b>Molecular Tour</b><br> | <b>Molecular Tour</b><br> | ||
| - | The crystal structure of selenomethionine-derivatised ''Streptomyces aureofaciens'' halogenase CtcP, which functions in chlortetracycline biosynthesis, is reported here at 2.7 Å resolution. The structure reveals a conserved monooxygenase domain and a unique C-terminal domain. The crystal structure of the CtcP protein from | + | The crystal structure of selenomethionine-derivatised ''Streptomyces aureofaciens'' halogenase CtcP, which functions in chlortetracycline biosynthesis, is reported here at 2.7 Å resolution. The structure reveals a conserved monooxygenase domain and a unique C-terminal domain. The crystal structure of the CtcP protein from ''Streptomyces aureofaciens'' ([[7xgb]]) is shown in cartoon representation in two different views: |
| - | ''Streptomyces aureofaciens'' ([[7xgb]]) is shown in cartoon representation in two different views: | + | |
*<scene name='91/915821/Cv/4'>1st view</scene>. | *<scene name='91/915821/Cv/4'>1st view</scene>. | ||
*<scene name='91/915821/Cv/3'>2nd view. Rotated ~ 90° clockwise around the horizontal axis, respective to the orientation shown at 1st view</scene>. The N- (green) and C- (blue) terminal domains of CtcP are color coded. | *<scene name='91/915821/Cv/3'>2nd view. Rotated ~ 90° clockwise around the horizontal axis, respective to the orientation shown at 1st view</scene>. The N- (green) and C- (blue) terminal domains of CtcP are color coded. | ||
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<scene name='91/915821/Cv/11'>The comparison of the substrates binding site in both CtcP and PltM</scene>. The enzymatic active center residues (K87 in PltM, K98 in CtcP) and the phloroglucinol from PltM structure are shown in ball-and-stick representation. The CtcP ([[7xgb]]) is colored in green and blue, while the PltM ([[6bza]]) is colored in white-smoke. | <scene name='91/915821/Cv/11'>The comparison of the substrates binding site in both CtcP and PltM</scene>. The enzymatic active center residues (K87 in PltM, K98 in CtcP) and the phloroglucinol from PltM structure are shown in ball-and-stick representation. The CtcP ([[7xgb]]) is colored in green and blue, while the PltM ([[6bza]]) is colored in white-smoke. | ||
| - | '''PDB reference:''' The crystal structure of the CtcP protein from | + | '''PDB reference:''' The crystal structure of the CtcP protein from ''Streptomyces aureofaciens'', [[7xgb]]. |
| - | ''Streptomyces aureofaciens'', [[7xgb]]. | + | |
<b>References</b><br> | <b>References</b><br> | ||
Revision as of 11:38, 29 June 2022
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This page complements a publication in scientific journals and is one of the Proteopedia's Interactive 3D Complement pages. For aditional details please see I3DC.
