DNA mismatch repair protein

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== Function ==
== Function ==
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'''DNA mismatch repair proteins''' are key players in genomic stability by signalling mismatches occurring during DNA replication and recombination<ref>PMID:21638687</ref> .< /br>
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'''DNA mismatch repair proteins''' are key players in genomic stability by signalling mismatches occurring during DNA replication and recombination<ref>PMID:21638687</ref> .< br/>
'''MutS''' is prokaryotic and recognizes base-base mismatches and small insertion/deletion mispairs.<br />
'''MutS''' is prokaryotic and recognizes base-base mismatches and small insertion/deletion mispairs.<br />
'''MutL''' enhances recognition of mismatches <br />
'''MutL''' enhances recognition of mismatches <br />

Revision as of 09:22, 30 June 2022

E. coli MutS complex with DNA and ATP (PDB id 7ai5)

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References

  1. Herraez A. Biomolecules in the computer: Jmol to the rescue. Biochem Mol Biol Educ. 2006 Jul;34(4):255-61. doi: 10.1002/bmb.2006.494034042644. PMID:21638687 doi:10.1002/bmb.2006.494034042644

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Michal Harel, Alexander Berchansky

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