7m4c
From Proteopedia
(Difference between revisions)
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| - | ==== | + | ==DNA Polymerase Lambda, TTP:At Mn2+ Product State Ternary Complex, 960 min== |
| - | <StructureSection load='7m4c' size='340' side='right'caption='[[7m4c]]' scene=''> | + | <StructureSection load='7m4c' size='340' side='right'caption='[[7m4c]], [[Resolution|resolution]] 1.95Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[7m4c]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7M4C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7M4C FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7m4c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7m4c OCA], [https://pdbe.org/7m4c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7m4c RCSB], [https://www.ebi.ac.uk/pdbsum/7m4c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7m4c ProSAT]</span></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PPV:PYROPHOSPHATE'>PPV</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7m4c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7m4c OCA], [https://pdbe.org/7m4c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7m4c RCSB], [https://www.ebi.ac.uk/pdbsum/7m4c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7m4c ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[https://www.uniprot.org/uniprot/DPOLL_HUMAN DPOLL_HUMAN]] Repair polymerase. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Has both DNA polymerase and terminal transferase activities. Has a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.<ref>PMID:11457865</ref> <ref>PMID:15537631</ref> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: | + | [[Category: Jamsen JA]] |
| + | [[Category: Wilson SH]] | ||
Revision as of 06:39, 8 September 2022
DNA Polymerase Lambda, TTP:At Mn2+ Product State Ternary Complex, 960 min
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