7m4k
From Proteopedia
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| - | ==== | + | ==DNA Polymerase Lambda, TTPaS:At Ca2+ Ground State Ternary Complex== |
| - | <StructureSection load='7m4k' size='340' side='right'caption='[[7m4k]]' scene=''> | + | <StructureSection load='7m4k' size='340' side='right'caption='[[7m4k]], [[Resolution|resolution]] 1.72Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[7m4k]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7M4K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7M4K FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7m4k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7m4k OCA], [https://pdbe.org/7m4k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7m4k RCSB], [https://www.ebi.ac.uk/pdbsum/7m4k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7m4k ProSAT]</span></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=YQS:[[(2~{R},3~{S},5~{R})-5-[5-methyl-2,4-bis(oxidanylidene)pyrimidin-1-yl]-3-oxidanyl-oxolan-2-yl]methoxy-sulfanyl-phosphoryl]+phosphono+hydrogen+phosphate'>YQS</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7m4k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7m4k OCA], [https://pdbe.org/7m4k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7m4k RCSB], [https://www.ebi.ac.uk/pdbsum/7m4k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7m4k ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[https://www.uniprot.org/uniprot/DPOLL_HUMAN DPOLL_HUMAN]] Repair polymerase. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Has both DNA polymerase and terminal transferase activities. Has a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.<ref>PMID:11457865</ref> <ref>PMID:15537631</ref> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: | + | [[Category: Jamsen JA]] |
| + | [[Category: Wilson SH]] | ||
Revision as of 06:39, 8 September 2022
DNA Polymerase Lambda, TTPaS:At Ca2+ Ground State Ternary Complex
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