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1hmj

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{{STRUCTURE_1hmj| PDB=1hmj | SCENE= }}
{{STRUCTURE_1hmj| PDB=1hmj | SCENE= }}
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'''SOLUTION STRUCTURE OF RNA POLYMERASE SUBUNIT H'''
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===SOLUTION STRUCTURE OF RNA POLYMERASE SUBUNIT H===
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==Overview==
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The archaeal H and eukaryotic RPB5 RNA polymerase subunits are highly homologous and are likely to play a fundamental role in transcription that extends from archaea to humans. We report the structure of subunit H, in solution, from the archaeon Methanococcus jannaschii using multidimensional nuclear magnetic resonance. The structure reveals a novel fold containing a four-stranded mixed beta sheet that is flanked on one side by three short helices. The dominant feature is beta-ribbon motif, which presents a hydrophobic, basic surface, and defines a general RNA polymerase architectural scaffold.
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{{ABSTRACT_PUBMED_10191143}}
==About this Structure==
==About this Structure==
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1HMJ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii Methanocaldococcus jannaschii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HMJ OCA].
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1HMJ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii Methanocaldococcus jannaschii]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HMJ OCA].
==Reference==
==Reference==
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[[Category: Rpb5]]
[[Category: Rpb5]]
[[Category: Subunit h]]
[[Category: Subunit h]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 19:01:00 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 08:24:12 2008''

Revision as of 05:24, 1 July 2008

Image:1hmj.png

Template:STRUCTURE 1hmj

SOLUTION STRUCTURE OF RNA POLYMERASE SUBUNIT H

Template:ABSTRACT PUBMED 10191143

About this Structure

1HMJ is a Single protein structure of sequence from Methanocaldococcus jannaschii. Full experimental information is available from OCA.

Reference

RNA polymerase subunit H features a beta-ribbon motif within a novel fold that is present in archaea and eukaryotes., Thiru A, Hodach M, Eloranta JJ, Kostourou V, Weinzierl RO, Matthews S, J Mol Biol. 1999 Apr 9;287(4):753-60. PMID:10191143

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