3tga
From Proteopedia
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<StructureSection load='3tga' size='340' side='right'caption='[[3tga]], [[Resolution|resolution]] 1.30Å' scene=''> | <StructureSection load='3tga' size='340' side='right'caption='[[3tga]], [[Resolution|resolution]] 1.30Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3tga]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[3tga]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rhodnius_prolixus Rhodnius prolixus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TGA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TGA FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.3Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr> |
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3tga FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tga OCA], [https://pdbe.org/3tga PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3tga RCSB], [https://www.ebi.ac.uk/pdbsum/3tga PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3tga ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3tga FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tga OCA], [https://pdbe.org/3tga PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3tga RCSB], [https://www.ebi.ac.uk/pdbsum/3tga PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3tga ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | + | [https://www.uniprot.org/uniprot/NP4_RHOPR NP4_RHOPR] Heme-based protein that deliver nitric oxide gas (NO) to the victim while feeding, resulting in vasodilation and inhibition of platelet aggregation. Also bind tightly to histamine, which is released by the host to induce wound healing (By similarity). | |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: | + | [[Category: Rhodnius prolixus]] |
| - | [[Category: He | + | [[Category: He C]] |
| - | [[Category: Knipp | + | [[Category: Knipp M]] |
| - | [[Category: Ogata | + | [[Category: Ogata H]] |
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Current revision
Crystal structure of L130R mutant of Nitrophorin 4 from Rhodnius prolixus at pH 7.4
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