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3tr5

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<StructureSection load='3tr5' size='340' side='right'caption='[[3tr5]], [[Resolution|resolution]] 2.11&Aring;' scene=''>
<StructureSection load='3tr5' size='340' side='right'caption='[[3tr5]], [[Resolution|resolution]] 2.11&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3tr5]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/"rickettsia_burneti"_(sic)_derrick_1939 "rickettsia burneti" (sic) derrick 1939]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TR5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TR5 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3tr5]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Coxiella_burnetii Coxiella burnetii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TR5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TR5 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.11&#8491;</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CBU_0811, prfC ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=777 "Rickettsia burneti" (sic) Derrick 1939])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3tr5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tr5 OCA], [https://pdbe.org/3tr5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3tr5 RCSB], [https://www.ebi.ac.uk/pdbsum/3tr5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3tr5 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3tr5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tr5 OCA], [https://pdbe.org/3tr5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3tr5 RCSB], [https://www.ebi.ac.uk/pdbsum/3tr5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3tr5 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/RF3_COXBU RF3_COXBU]] Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.[HAMAP-Rule:MF_00072]
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[https://www.uniprot.org/uniprot/RF3_COXBU RF3_COXBU] Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.[HAMAP-Rule:MF_00072]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Coxiella burnetii]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Burshteyn, F]]
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[[Category: Burshteyn F]]
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[[Category: Cassidy, M]]
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[[Category: Cassidy M]]
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[[Category: Cheung, J]]
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[[Category: Cheung J]]
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[[Category: Franklin, M C]]
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[[Category: Franklin MC]]
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[[Category: Gary, E]]
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[[Category: Gary E]]
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[[Category: Love, J]]
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[[Category: Love J]]
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[[Category: Rudolph, M]]
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[[Category: Rudolph M]]
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[[Category: Protein synthesis]]
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[[Category: Translation]]
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Revision as of 08:16, 6 December 2023

Structure of a peptide chain release factor 3 (prfC) from Coxiella burnetii

PDB ID 3tr5

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