5ssw

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m (Protected "5ssw" [edit=sysop:move=sysop])
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'''Unreleased structure'''
 
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The entry 5ssw is ON HOLD until Paper Publication
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==DHFR:NADP+:FOL complex at 270 K (multi-crystal)==
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<StructureSection load='5ssw' size='340' side='right'caption='[[5ssw]], [[Resolution|resolution]] 1.06&Aring;' scene=''>
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Authors: Greisman, J.B., Dalton, K.M., Brookner, D.E., Hekstra, D.R.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5ssw]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5SSW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5SSW FirstGlance]. <br>
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Description: DHFR:NADP+:FOL complex at 270 K (multi-crystal)
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.06&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CSD:3-SULFINOALANINE'>CSD</scene>, <scene name='pdbligand=FOL:FOLIC+ACID'>FOL</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
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[[Category: Greisman, J.B]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ssw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ssw OCA], [https://pdbe.org/5ssw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ssw RCSB], [https://www.ebi.ac.uk/pdbsum/5ssw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ssw ProSAT]</span></td></tr>
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[[Category: Dalton, K.M]]
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</table>
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[[Category: Hekstra, D.R]]
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== Function ==
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[[Category: Brookner, D.E]]
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[https://www.uniprot.org/uniprot/DYR_ECOLI DYR_ECOLI] Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
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__TOC__
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</StructureSection>
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[[Category: Escherichia coli K-12]]
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[[Category: Large Structures]]
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[[Category: Brookner DE]]
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[[Category: Dalton KM]]
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[[Category: Greisman JB]]
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[[Category: Hekstra DR]]

Revision as of 05:51, 23 August 2023

DHFR:NADP+:FOL complex at 270 K (multi-crystal)

PDB ID 5ssw

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