7fbi
From Proteopedia
(Difference between revisions)
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| - | ==== | + | ==Cryo-EM structure of EBV gB in complex with nAbs 3A3 and 3A5== |
| - | <StructureSection load='7fbi' size='340' side='right'caption='[[7fbi]]' scene=''> | + | <StructureSection load='7fbi' size='340' side='right'caption='[[7fbi]], [[Resolution|resolution]] 3.90Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[7fbi]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_gammaherpesvirus_4 Human gammaherpesvirus 4] and [https://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7FBI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7FBI FirstGlance]. <br> |
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7fbi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7fbi OCA], [https://pdbe.org/7fbi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7fbi RCSB], [https://www.ebi.ac.uk/pdbsum/7fbi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7fbi ProSAT]</span></td></tr> | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7fbi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7fbi OCA], [https://pdbe.org/7fbi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7fbi RCSB], [https://www.ebi.ac.uk/pdbsum/7fbi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7fbi ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[https://www.uniprot.org/uniprot/R4R670_EBVG R4R670_EBVG]] Envelope glycoprotein that forms spikes at the surface of virion envelope. Essential for the initial attachment to heparan sulfate moities of the host cell surface proteoglycans. Involved in fusion of viral and cellular membranes leading to virus entry into the host cell. Following initial binding to its host receptors, membrane fusion is mediated by the fusion machinery composed at least of gB and the heterodimer gH/gL. May be involved in the fusion between the virion envelope and the outer nuclear membrane during virion egress.[HAMAP-Rule:MF_04032] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Human gammaherpesvirus 4]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Z | + | [[Category: Oryctolagus cuniculus]] |
| + | [[Category: Chen Y]] | ||
| + | [[Category: Hong J]] | ||
| + | [[Category: Li S]] | ||
| + | [[Category: Zha Z]] | ||
| + | [[Category: Zhang X]] | ||
| + | [[Category: Zheng Q]] | ||
Revision as of 05:40, 8 September 2022
Cryo-EM structure of EBV gB in complex with nAbs 3A3 and 3A5
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