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3u9x
From Proteopedia
(Difference between revisions)
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<StructureSection load='3u9x' size='340' side='right'caption='[[3u9x]], [[Resolution|resolution]] 1.80Å' scene=''> | <StructureSection load='3u9x' size='340' side='right'caption='[[3u9x]], [[Resolution|resolution]] 1.80Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3u9x]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[3u9x]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3U9X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3U9X FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=LLP:(2S)-2-AMINO-6-[[3-HYDROXY-2-METHYL-5-(PHOSPHONOOXYMETHYL)PYRIDIN-4-YL]METHYLIDENEAMINO]HEXANOIC+ACID'>LLP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> |
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3u9x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3u9x OCA], [https://pdbe.org/3u9x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3u9x RCSB], [https://www.ebi.ac.uk/pdbsum/3u9x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3u9x ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3u9x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3u9x OCA], [https://pdbe.org/3u9x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3u9x RCSB], [https://www.ebi.ac.uk/pdbsum/3u9x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3u9x ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | + | [https://www.uniprot.org/uniprot/1433S_HUMAN 1433S_HUMAN] Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway (By similarity). p53-regulated inhibitor of G2/M progression. | |
==See Also== | ==See Also== | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Kohlbacher | + | [[Category: Kohlbacher O]] |
| - | [[Category: Ottmann | + | [[Category: Ottmann C]] |
| - | [[Category: Roeglin | + | [[Category: Roeglin L]] |
| - | [[Category: Thiel | + | [[Category: Thiel P]] |
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Current revision
Covalent attachment of pyridoxal-phosphate derivatives to 14-3-3 proteins
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