7xy8
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of antibody Fab fragment in complex with CD147(EMMPIRIN)== | |
| - | + | <StructureSection load='7xy8' size='340' side='right'caption='[[7xy8]], [[Resolution|resolution]] 2.30Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[7xy8]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7XY8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7XY8 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7xy8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7xy8 OCA], [https://pdbe.org/7xy8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7xy8 RCSB], [https://www.ebi.ac.uk/pdbsum/7xy8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7xy8 ProSAT]</span></td></tr> | |
| - | [[Category: | + | </table> |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/BASI_HUMAN BASI_HUMAN] Plays an important role in targeting the monocarboxylate transporters SLC16A1, SLC16A3 and SLC16A8 to the plasma membrane. Plays pivotal roles in spermatogenesis, embryo implantation, neural network formation and tumor progression. Stimulates adjacent fibroblasts to produce matrix metalloproteinases (MMPS). Seems to be a receptor for oligomannosidic glycans. In vitro, promotes outgrowth of astrocytic processes.<ref>PMID:17127621</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Synthetic construct]] | ||
| + | [[Category: Amano M]] | ||
| + | [[Category: Fukuchi K]] | ||
| + | [[Category: Nakamura K]] | ||
| + | [[Category: Suzuki M]] | ||
| + | [[Category: Yoneda K]] | ||
Revision as of 10:09, 24 November 2022
Crystal structure of antibody Fab fragment in complex with CD147(EMMPIRIN)
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