7oyc

==Cryo-EM structure of the Xenopus egg 80S ribosome==

<StructureSection load='7oyc' size='340' side='right'caption='[[7oyc]], [[Resolution|resolution]] 2.40&Aring;' scene=''>

<table><tr><td colspan='2'>[[7oyc]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Xenopus_laevis Xenopus laevis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7OYC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7OYC FirstGlance]. <br>

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5CT:HYPUSINE'>5CT</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7oyc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7oyc OCA], [https://pdbe.org/7oyc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7oyc RCSB], [https://www.ebi.ac.uk/pdbsum/7oyc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7oyc ProSAT]</span></td></tr>

== Function ==

[[https://www.uniprot.org/uniprot/Q7ZXG3_XENLA Q7ZXG3_XENLA]] mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Critical for the efficient synthesis of peptide bonds between consecutive proline residues. Can resolve ribosomal stalling caused by consecutive prolines during translation. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis.[RuleBase:RU362005]

[[Category: Xenopus laevis]]

[[Category: Lorenzo-Orts L]]

[[Category: Pauli A]]